4-Fluoro-2-Nitroaniline Synthesis Route & Industrial Purity Guide
The global demand for fluorinated aniline derivatives continues to surge across pharmaceutical and agrochemical sectors, driven by the need for high-performance intermediates. Supply chain stability remains a critical priority for procurement executives seeking reliable partners for large-scale production. As a leading 4-Fluoro-2-Nitroaniline Bulk Price Global Manufacturer, we understand the complexities of sourcing chemicals that meet rigorous quality standards. Ensuring consistent industrial purity and stable supply is essential for maintaining downstream production efficiency in dye manufacturing and material science applications.
Detailed Chemical Synthesis Route and Reaction Mechanism
The production of 4-Fluoro-2-nitroaniline typically involves the selective nitration of 4-fluoroaniline or the reduction of corresponding dinitro compounds. The synthesis route requires precise temperature control to minimize the formation of isomeric by-products, ensuring the final product meets strict industrial purity specifications. Chemists focus on optimizing reaction conditions to maximize yield while maintaining the integrity of the fluoro substituent. This process demands advanced manufacturing capabilities to handle exothermic reactions safely and efficiently. Our technical team supports custom synthesis requirements, ensuring the reaction mechanism aligns with specific client needs for pharmaceutical development and coordination chemistry applications.
Technical Specifications and Analytical Methods
Quality assurance is paramount for R&D departments verifying material suitability. Each batch undergoes rigorous analytical testing using HPLC and GC-MS to confirm composition. The following table outlines the standard technical parameters expected for commercial-grade material:
| Parameter | Specification |
| CAS Number | 364-78-3 |
| Chemical Name | 4-Fluoro-2-nitroaniline |
| Molecular Formula | C6H5FN2O2 |
| Formula Weight | 156.12 |
| Purity (HPLC) | ≥ 98% |
| Melting Point | 90°C to 94°C |
| Appearance | Yellow to Orange Crystalline Powder |
| Solubility | Insoluble in water |
| EINECS Number | 206-666-0 |
Verification of these specs is documented in the Certificate of Analysis (COA), which is available for every shipment. NINGBO INNO PHARMCHEM CO.,LTD. ensures that all technical data aligns with international safety and quality regulations, providing peace of mind for procurement teams managing global logistics.
Industrial Packaging Options and Global Logistics Handling
Safe transport and storage are critical for maintaining product integrity during transit. We offer flexible industrial packaging options, including 25kg fiber drums and larger IBCs for bulk orders, designed to protect against moisture and contamination. Our logistics team coordinates secure shipping methods compliant with hazardous material regulations, ensuring timely delivery to ports worldwide. Proper storage at ambient temperatures is recommended to maintain stability, as the material is incompatible with strong oxidizing agents and strong bases. Our commitment to stable supply means minimizing lead times while adhering to all safety protocols for handling fluorinated compounds.
Partnering with an experienced supplier ensures access to high-quality intermediates for azo dyes, herbicides, and pharmaceutical agents. We prioritize long-term relationships built on transparency and technical excellence.
To request a batch-specific COA, SDS, or secure a bulk pricing quote, please contact our technical sales team.