Industrial Purity 4-Fluorobutan-1-Ol Specifications and Bulk Procurement Guide
- High Assay Standards: Target purity levels exceeding 99.0% for sensitive organic synthesis applications.
- Supply Chain Stability: Reliable bulk price structures and consistent manufacturing process outputs.
- Safety Compliance: Full adherence to GHS02 and GHS07 hazard standards with comprehensive documentation.
In the realm of fine chemical manufacturing and pharmaceutical intermediate production, the quality of fluorinated alcohols is paramount. 4-Fluorobutan-1-ol serves as a critical building block for various agrochemical and medicinal compounds. As demand scales, the focus shifts from gram-scale research quantities to metric-ton industrial supplies. Ensuring consistent industrial purity requires a robust understanding of the underlying manufacturing process and strict quality control protocols. NINGBO INNO PHARMCHEM CO.,LTD. stands as a premier global manufacturer dedicated to supplying these high-specification intermediates to the international market.
Technical Specifications and Physical Properties
For procurement officers and process chemists, verifying the physical constants against the Certificate of Analysis (COA) is the first step in vendor qualification. The molecular structure, defined by the formula C4H9FO, dictates the reactivity and handling requirements. Below is the standard technical data sheet information expected for high-grade material.
| Property | Specification |
|---|---|
| Chemical Name | 4-Fluorobutan-1-ol |
| CAS Number | 61599-24-4 |
| Molecular Formula | C4H9FO |
| Molecular Weight | 92.11 g/mol |
| HS Code | 2905599890 |
| Purity Standard | ≥ 99.0% (GC Area) |
Deviation in molecular weight or purity often indicates the presence of isomers or incomplete reaction byproducts. In large-scale operations, even minor impurities can catalyze unwanted side reactions downstream, affecting overall reaction yields. Therefore, sourcing from a validated supplier who guarantees these specifications is essential for maintaining process efficiency.
Optimizing the Synthesis Route for Industrial Scale
The commercial viability of fluorinated intermediates depends heavily on the efficiency of the synthesis route. Traditional laboratory methods may not translate directly to industrial reactors due to heat transfer limitations and safety constraints associated with fluorinating agents. A scalable manufacturing process must balance cost-effectiveness with safety.
Modern production techniques focus on nucleophilic substitution strategies that minimize halogenated waste. The goal is to achieve a clean profile that reduces the burden on purification units such as fractional distillation columns. When evaluating potential suppliers, buyers should inquire about the specific methodology used to ensure residual starting materials are below detectable limits. For researchers requiring detailed technical data sheets or specific batch records for 4-Fluorobutanol, direct consultation with the manufacturing technical team is recommended.
Consistency in the synthesis route ensures that every batch behaves predictably in downstream coupling reactions. This reliability is a hallmark of NINGBO INNO PHARMCHEM CO.,LTD., where process parameters are tightly controlled to prevent batch-to-batch variability.
Safety Handling and Regulatory Compliance
Handling fluorinated alcohols requires strict adherence to safety protocols. Based on global harmonized system standards, this chemical typically carries specific hazard classifications that must be managed during storage and transport.
- GHS Symbols: GHS02 (Flammable), GHS07 (Warning)
- Signal Word: Warning
- Hazard Statements: H226 (Flammable liquid and vapor), H302 (Harmful if swallowed), H315 (Causes skin irritation), H319 (Causes serious eye irritation), H335 (May cause respiratory irritation).
- Precautionary Statements: P210 (Keep away from heat/sparks/open flames), P261 (Avoid breathing dust/fume/gas/mist/vapors/spray), P280 (Wear protective gloves/protective clothing/eye protection/face protection).
Proper storage involves keeping containers tightly closed in a cool, well-ventilated area away from incompatible materials such as strong oxidizing agents. Transport classification usually falls under flammable liquid categories, requiring appropriate UN packaging for international shipping. A comprehensive COA should always accompany the shipment, detailing not just purity but also confirming that safety tests have been conducted.
Commercial Considerations and Bulk Pricing
The market for fine chemical intermediates is dynamic, with bulk price fluctuations often tied to raw material availability and energy costs. Unlike retail chemical suppliers who focus on milligram quantities, industrial buyers require stability in supply chains. Pricing models for metric-ton quantities differ significantly from gram-scale pricing found in research catalogs.
When analyzing market data, it is evident that suppliers offering consistent industrial purity at competitive rates are limited. Many vendors act as traders rather than producers, which can introduce variability in quality. A true global manufacturer provides transparency regarding production capacity and lead times. Buyers should expect tiered pricing structures that reflect volume commitments, ensuring cost-efficiency for large-scale synthesis campaigns.
Furthermore, the ability to provide custom packaging and flexible logistics solutions is a key differentiator. Whether shipping in drums or isotanks, the integrity of the chemical must be maintained to prevent moisture uptake, which can degrade quality over time. NINGBO INNO PHARMCHEM CO.,LTD. ensures that all bulk orders are sealed under inert atmospheres when necessary to preserve the manufacturing process standards achieved during production.
Conclusion
Securing a reliable supply of 4-Fluorobutan-1-ol is a strategic decision for any chemical manufacturing enterprise. By prioritizing industrial purity, verified synthesis route documentation, and robust safety compliance, companies can mitigate production risks. Partnering with an experienced entity like NINGBO INNO PHARMCHEM CO.,LTD. ensures access to high-quality intermediates that meet the rigorous demands of modern pharmaceutical and agrochemical synthesis. For detailed inquiries regarding specifications or to request a sample for qualification, contact the sales team directly to discuss your specific volume requirements.