Intermediates

4-Fluorobutanol

  • CAS No.61599-24-4
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 4-Fluorobutanol (CAS 61599-24-4) is a versatile fluorinated alcohol widely used as an intermediate in organic synthesis and pharmaceutical R&D.

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Product Technical Details

Product Overview

4-Fluorobutanol (CAS 61599-24-4), also known as 4-Fluorobutan-1-ol, is a colorless liquid belonging to the class of fluorinated aliphatic alcohols. With a molecular formula of C4H9FO and a molecular weight of 92.11 g/mol, it serves as a critical building block in advanced organic synthesis. Its unique structure—featuring a terminal hydroxyl group and a fluorine atom at the gamma position—enables diverse reactivity profiles, making it particularly valuable in the development of complex pharmaceutical intermediates and specialty agrochemicals.

Specifications

AppearanceColorless liquid
Assay≥99.0%
Moisture≤0.5%
Molecular FormulaC4H9FO
Molecular Weight92.11 g/mol

Industrial Applications

As a high-purity fluorinated intermediate, 4-Fluorobutanol is primarily employed in research and industrial-scale organic synthesis. Key application areas include:

  • Serving as a precursor in the preparation of fluorinated heterocycles and bioactive molecules
  • Facilitating the construction of carbon-fluorine frameworks in medicinal chemistry campaigns
  • Acting as a functional handle for further derivatization via esterification, etherification, or oxidation pathways

Due to its reactivity and stability balance, it is especially suited for multi-step syntheses requiring orthogonal functional group tolerance.

Handling and Storage

This compound should be stored in a cool, dry, and well-ventilated area, away from heat sources and incompatible materials such as strong oxidizing agents. Standard industrial hygiene practices, including the use of gloves and eye protection, are recommended during handling. Packaging is typically provided in 200 kg drums, with custom packaging options available upon request to meet specific logistical or regulatory requirements.