3,6-Dichloropyridazine Bulk Price 2026: Market Analysis and Procurement Guide
- Industrial purity standards typically exceed 98% for API intermediate applications.
- 2026 pricing is driven by raw material volatility and synthesis route efficiency.
- Reliable global manufacturers provide comprehensive COA documentation for bulk orders.
In the landscape of pharmaceutical intermediates, 3,6-Dichloropyridazine (CAS: 141-30-0) remains a critical building block for the synthesis of heterocyclic compounds. As we approach 2026, procurement managers and process chemists must navigate fluctuating market dynamics to secure cost-effective supply chains. This compound, also known chemically as 3,6-Dichloro-1,2-diazine, is essential for preparing alfa-(halohetaroyl)-2-azahetarylacetonitriles and various active pharmaceutical ingredients. For organizations seeking reliability, partnering with a established entity like NINGBO INNO PHARMCHEM CO.,LTD. ensures access to high-quality materials that meet rigorous international standards.
Current Bulk Pricing Trends for 3,6-Dichloropyridazine
The bulk price of 3,6-Dichloropyridazine is influenced by several macroeconomic and microeconomic factors. Historically, laboratory-scale packages (e.g., 25g to 500g) command significantly higher unit costs compared to industrial drum quantities. In the 2026 market forecast, pricing stability is expected to correlate closely with the availability of precursor pyridazine derivatives. Suppliers who maintain robust inventory levels can offer more competitive rates, mitigating the risk of production delays.
Market data indicates that purity levels directly impact cost structures. While standard reagent grade may suffice for initial R&D, commercial scale-up requires industrial purity consistent with Good Manufacturing Practice (GMP) guidelines. Specifications often dictate a minimum assay of 98%, with strict limits on impurities that could affect downstream reaction yields. Buyers should anticipate that prices for certified high-purity batches will remain premium compared to technical grade materials, reflecting the additional purification steps required during production.
Factors Influencing Industrial-Grade Pricing in 2026
Several technical variables drive the final cost per kilogram for this diazine derivative. Understanding these factors allows procurement teams to negotiate better terms and validate supplier quotations.
1. Synthesis Route Efficiency
The chemical pathway used to produce 3,6-Dichloropyridazine significantly affects yield and waste management costs. Efficient chlorination of the pyridazine ring minimizes byproduct formation, thereby reducing purification expenses. When evaluating suppliers, understanding the specific manufacturing process ensures consistency in batch-to-batch quality. Processes that utilize advanced catalytic systems often result in higher overall yields, which can be passed down as cost savings to the bulk buyer.
2. Regulatory Compliance and Safety
Handling hazardous chemicals requires strict adherence to safety protocols. 3,6-Dichloropyridazine is classified with specific hazard statements, including toxicity if inhaled or swallowed (H301, H331) and skin irritation (H315). Compliance with transport regulations, such as UN2811 for toxic solids, adds logistical costs. Suppliers who manage these compliance issues internally reduce the administrative burden on the purchaser, adding value beyond the base chemical price.
3. Raw Material Volatility
The cost of chlorinating agents and the base pyridazine scaffold fluctuates based on global chemical supply chains. A global manufacturer with diversified sourcing capabilities can buffer against regional shortages. In 2026, expect pricing models to include clauses for raw material adjustments, making long-term contracts advantageous for stable budgeting.
Technical Specifications and Quality Control
To ensure the material meets your synthetic requirements, verify the Certificate of Analysis (COA) against standard physical properties. The following table outlines the typical specifications expected for high-quality 3,6-Dichloropyridazine suitable for pharmaceutical intermediates.
| Parameter | Specification |
|---|---|
| Chemical Name | 3,6-Dichloropyridazine |
| CAS Number | 141-30-0 |
| Molecular Formula | C4H2Cl2N2 |
| Formula Weight | 148.98 g/mol |
| Melting Point | 66°C to 70°C |
| Purity (Assay) | ≥ 98.0% |
| Solubility | Soluble in chloroform; Insoluble in water |
| Appearance | White to off-white crystalline powder |
| Storage Conditions | Ambient temperatures, protected from light |
Attention to the melting point range is critical; deviations outside 66°C to 70°C often indicate the presence of isomeric impurities or incomplete reaction conversion. Furthermore, solubility profiles must match technical data sheets to ensure compatibility with intended solvent systems during synthesis.
How to Source Cost-Effective High-Purity 3,6-Dichloropyridazine
Sourcing this intermediate requires a strategic approach to vendor selection. It is not merely about finding the lowest unit price but ensuring supply continuity and technical support. A reputable global manufacturer will provide full traceability from raw materials to the finished product. This transparency is vital for regulatory filings in the pharmaceutical sector.
When requesting quotes, specify your required industrial purity levels and packaging needs. Bulk procurement, such as multi-drum orders, typically unlocks significant pricing tiers compared to smaller catalog sizes. Additionally, verify that the supplier can provide updated safety data sheets and compliance documentation relevant to your region. Companies like NINGBO INNO PHARMCHEM CO.,LTD. specialize in bridging the gap between laboratory research and commercial production, offering the scalability needed for growing API demands.
In conclusion, the 3,6-Dichloropyridazine market in 2026 will reward buyers who prioritize technical verification and strategic partnerships. By focusing on the synthesis route efficiency and demanding rigorous COA validation, procurement teams can secure a stable supply chain. Whether for academic research or large-scale API production, ensuring the quality of this diazine intermediate is paramount to the success of the final pharmaceutical product.