(5-Formylfuran-2-Yl)Boronic Acid Bulk Price Global Manufacturer 2026

• Technical Grade Supply: Consistent industrial purity levels suitable for Suzuki coupling and pharmaceutical intermediate synthesis.
• Scalable Production: Optimized synthesis route ensuring high yields for kilogram to ton-scale procurement.
• 2026 Pricing Stability: Tiered bulk price models available with flexible Incoterms for global logistics.

Technical Overview and Pharmaceutical Applications

(5-Formylfuran-2-yl)boronic acid, identified by CAS number 27329-70-0, serves as a critical bifunctional reagent in modern organic synthesis. This compound features a furan ring substituted with both a formyl group and a boronic acid moiety, making it highly versatile for constructing π-extended heteroarylfuran systems. In the context of medicinal chemistry, this molecule is a key reactant involved in Suzuki coupling reactions, which are essential for the synthesis of stable dye-sensitized solar cells and complex biologically active molecules.

The utility of this chemical extends into high-value therapeutic areas. It is frequently employed in the heteroarylation processes required for the synthesis of HIF-1 inhibitors, which are investigated for cancer therapy. Furthermore, it acts as a precursor for disalicylic acid-furanyl derivatives designed to inhibit ephrin binding, as well as HIV-1 integrase inhibitors and epidermal growth factor receptor inhibitors. Due to the presence of the aldehyde functionality, careful handling is required to prevent unwanted side reactions during scale-up. Alternative nomenclature often encountered in procurement documents includes 5-formyl-2-furylboronic acid or 2-Formylfuran-5-Boronic Acid, though the IUPAC designation remains the standard for regulatory compliance.

Manufacturing Process and Industrial Purity Standards

Achieving consistent quality in bulk production requires a robust manufacturing process. The standard synthesis route typically involves the lithiation of protected furan derivatives followed by quenching with trialkyl borates and subsequent hydrolysis. However, maintaining the integrity of the formyl group during these steps is challenging. Advanced producers utilize cryogenic conditions and strict inert atmosphere protocols to maximize reaction yields and minimize decomposition.

For industrial applications, industrial purity is a paramount consideration. While research-grade samples may show 95% purity, bulk pharmaceutical intermediates often require tighter specifications regarding residual solvents and metal content. The compound is air-sensitive and insoluble in water, necessitating storage under inert gas such as nitrogen or argon. Decomposition typically begins around 140°C, so temperature control during drying and packaging is critical. A comprehensive Certificate of Analysis (COA) should accompany every shipment, detailing assay values, water content, and impurity profiles to ensure compatibility with downstream GMP processes.

Tiered Bulk Pricing Models for 25kg Drum Orders

Procurement strategies for fine chemicals in 2026 must account for volatility in raw material costs and logistics. A global manufacturer typically offers tiered pricing structures that incentivize larger volume commitments. For (5-Formylfuran-2-yl)boronic Acid, pricing is generally segmented by weight classes, such as 1kg, 5kg, 25kg, and 200kg drums. Buyers committing to annual contracts for 25kg drum orders can secure significantly reduced rates compared to spot purchases.

When sourcing high-purity (5-Formylfuran-2-yl)boronic Acid, buyers should evaluate the total cost of ownership, which includes packaging integrity and stability testing. Bulk price negotiations should also consider the cost of specialized packaging required for air-sensitive materials. Double-layered bagging within fiber drums, often flushed with nitrogen, adds to the unit cost but prevents degradation during transit. Suppliers who can demonstrate a stable supply chain despite geopolitical shifts will command a premium, yet offer greater security of supply for critical pipeline projects.

Global Manufacturer Supply Chain and MOQ Requirements

Reliability in the supply chain is as important as the chemical specifications themselves. NINGBO INNO PHARMCHEM CO.,LTD. operates as a premier global manufacturer, ensuring that minimum order quantity (MOQ) requirements are aligned with both pilot-scale research and commercial production needs. For standard intermediates, the MOQ may start at 1kg for evaluation, but commercial terms usually apply to orders exceeding 10kg. Lead times vary based on inventory status, with stock items shipping within 3-5 days and custom synthesis batches requiring 2-4 weeks.

Logistics for air-sensitive chemicals require adherence to strict safety regulations. The material is classified with hazard statements H315, H319, and H335, indicating potential skin, eye, and respiratory irritation. Therefore, shipping documentation must accurately reflect these hazards to avoid customs delays. A capable global manufacturer will handle export licensing, dangerous goods declarations, and coordinate with freight forwarders experienced in handling chemical powders. This end-to-end management reduces the administrative burden on the procurement team and ensures timely delivery to facilities in Europe, North America, and Asia.

Technical Specifications Table

Property	Specification
Chemical Name	(5-Formylfuran-2-yl)boronic Acid
CAS Number	27329-70-0
Molecular Formula	C5H5BO4
Formula Weight	139.9 g/mol
Purity (HPLC)	≥ 95.0% (Customizable up to 98%)
Melting Point	∼140°C (decomposition)
Solubility	Insoluble in water; Soluble in organic solvents
Sensitivity	Air Sensitive (Store under inert gas)
Storage Condition	Cool, dry, well-ventilated, ambient temperatures

Requesting Custom Quotes and Incoterms for 2026

Forward planning for 2026 involves locking in supply contracts that mitigate currency fluctuation and raw material scarcity. Procurement officers should request custom quotes that specify Incoterms such as FOB, CIF, or DDP based on their logistical capabilities. For a global manufacturer, offering DDP (Delivered Duty Paid) services can streamline the import process for buyers lacking dedicated customs brokerage teams. Additionally, requesting batch-specific COA samples prior to bulk ordering is a standard best practice to verify industrial purity claims.

NINGBO INNO PHARMCHEM CO.,LTD. emphasizes transparency in its quoting process, providing detailed breakdowns of manufacturing costs, packaging fees, and freight estimates. This level of detail allows buyers to accurately budget for R&D projects or commercial production runs. By establishing a partnership with a verified supplier, companies can ensure a steady flow of critical intermediates like 5-formyl-2-furylboronic acid without interruptions. As the demand for furan-based heterocycles grows in the pharmaceutical and materials science sectors, securing a reliable supply chain now is essential for maintaining competitive advantage in the coming years.