High-Quality 2-Chlorotrityl Chloride Resin: A Key Solid Support for Peptide Synthesis and Organic Chemistry

Discover the advantages of 2-Chlorotrityl Chloride Resin for your demanding peptide synthesis and complex organic chemistry projects. As a leading supplier, we provide this essential solid support to ensure your research and manufacturing processes are efficient and successful.

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Key Advantages of Our 2-Chlorotrityl Chloride Resin

Superior Mild Cleavage

The 2-chlorotrityl moiety allows for the cleavage of synthesized compounds using very mild acidic conditions (e.g., 1-5% TFA in DCM). This is crucial for preserving acid-sensitive functionalities in your target molecules, a significant advantage when looking to buy specialized synthesis reagents.

Minimized Side Reactions

The steric bulk of the 2-chlorotrityl group effectively inhibits diketopiperazine (DKP) formation, particularly important for peptides with C-terminal proline. This feature enhances the purity of your synthesized peptides, making it a preferred choice for peptide manufacturers.

Versatile Application Range

This resin is highly versatile, suitable for Fmoc/tBu solid-phase peptide synthesis, and also widely used in the synthesis of various small organic molecules. Its compatibility with different chemistries makes it a valuable addition to any research or production facility.

Diverse Applications in Chemical Synthesis

Solid-Phase Peptide Synthesis (SPPS)

Ideal for preparing protected peptide fragments, essential for convergent synthesis strategies. Researchers often buy this to ensure high purity and efficient coupling in their peptide production workflows.

Small Molecule Synthesis

A robust support for immobilizing various organic building blocks, facilitating the creation of diverse compound libraries for drug discovery and development. Purchase this resin for your small molecule synthesis needs.

Custom Synthesis Projects

Its reliable performance and mild cleavage make it a preferred choice for custom organic synthesis and pharmaceutical intermediate manufacturing, ensuring successful project outcomes.

Linker Chemistry

The 2-chlorotrityl group can be further functionalized, allowing for the introduction of specific cleavage sites or functionalities, further broadening its application in advanced chemical synthesis.