Propargyl Carbonate N-Hydroxysuccinimide Ester: A Key Reagent in Peptide Synthesis and Bioconjugation
Discover the critical role of Propargyl Carbonate N-Hydroxysuccinimide Ester in modern peptide synthesis and bioconjugation. Learn how this high-purity chemical intermediate facilitates efficient amide bond formation and enables advanced click chemistry applications.
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Propargyl Carbonate N-Hydroxysuccinimide Ester
We are a reliable supplier in China offering high-purity Propargyl Carbonate N-Hydroxysuccinimide Ester. This compound is essential for advancing peptide synthesis, serving as a vital activated ester for creating amide bonds with high efficiency. Its structure incorporates a propargyl group, making it a versatile tool for bioconjugation reactions through click chemistry. As a leading manufacturer in China, we ensure quality and consistency for your research and development needs.
- Facilitating Efficient Peptide Synthesis: This reagent plays a crucial role in various peptide synthesis protocols, enabling the formation of amide bonds with reduced racemization, a key challenge in achieving pure peptide sequences.
- Leveraging Click Chemistry for Bioconjugation: The presence of the propargyl group makes this ester an ideal candidate for copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions, allowing for precise conjugation with biomolecules.
- Ensuring High Purity and Quality: Our commitment as a supplier in China guarantees a product with 98% HPLC purity, providing reliable results in your sensitive synthetic processes and bioconjugation strategies.
- Versatile Application in Chemical Synthesis: Beyond peptide synthesis, this activated ester can be employed in a range of organic synthesis applications requiring selective amide bond formation.
Key Advantages
Enhanced Coupling Efficiency
The N-hydroxysuccinimide ester moiety provides excellent reactivity, ensuring efficient coupling reactions, which is crucial for successful peptide synthesis using this key reagent.
Reduced Racemization in Peptide Synthesis
This compound is known to minimize epimerization during peptide bond formation, a vital characteristic for synthesizing enantiomerically pure peptides and advancing peptide synthesis protocols.
Versatile Bioconjugation Tool
The propargyl functional group is highly valuable for click chemistry, offering a straightforward pathway for attaching this molecule to biomolecules in bioconjugation applications.
Key Applications
Peptide Synthesis
A primary application is in the synthesis of peptides, where its activated ester form facilitates the formation of peptide bonds, contributing to the field of advanced peptide synthesis.
Bioconjugation
The propargyl group enables click chemistry reactions for conjugating molecules to proteins, antibodies, or nucleic acids, a key aspect of modern bioconjugation.
Organic Synthesis
Used as a versatile building block in organic synthesis for creating amide linkages in various complex molecules, showcasing its utility beyond traditional peptide synthesis.
Chemical Linkers
This compound can serve as a chemical linker, connecting different molecular entities through its reactive ester and propargyl functionalities, vital for various research applications.