Peptides & Building Blocks

N-Boc-Glycine Methyl Ester

  • CAS No.31954-27-5
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

A high-purity protected amino acid derivative essential for pharmaceutical synthesis and organic chemistry applications.

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Product Technical Details

Product Overview

N-Boc-Glycine Methyl Ester stands as a pivotal protected amino acid derivative within the realm of advanced organic synthesis. This chemical building block features a tert-butoxycarbonyl (Boc) protecting group on the nitrogen atom of glycine, coupled with a methyl ester functionality. Such structural configuration ensures stability during complex multi-step synthesis reactions, making it an indispensable reagent for pharmaceutical manufacturers and research laboratories globally. Our facility produces this compound under stringent quality control measures to guarantee consistency and reliability for downstream applications.

Technical Specifications

We adhere to rigorous industry standards to ensure that every batch meets the required chemical properties for sensitive synthetic processes. The following table outlines the key physical and chemical parameters associated with this product.

ParameterSpecification
CAS Number31954-27-5
Molecular FormulaC8H15NO4
Molecular Weight189.21 g/mol
AppearanceWhite Powder
Purity≥98.0%
Density1.28 g/cm3
Boiling Point190°C at 760 mmHg
Flash Point109°C

Industrial Applications

This protected glycine derivative is primarily utilized as a critical intermediate in the synthesis of complex pharmaceutical agents. It serves as a fundamental building block in peptide coupling reactions where the temporary protection of the amino group is required to prevent unwanted side reactions. The compound is extensively employed in the manufacturing of neurological therapeutic agents and GABA analogues. Furthermore, it finds application in the development of antioxidants and various fine chemical preparations. The high stability of the Boc group allows for versatile deprotection strategies, facilitating efficient workflow in medicinal chemistry and process development scales.

Quality Assurance and Manufacturing

Our production process emphasizes industrial purity and reproducibility. Each lot undergoes comprehensive analytical testing, including HPLC and NMR spectroscopy, to verify structural integrity and impurity profiles. We provide a Certificate of Analysis (COA) with every shipment, ensuring full transparency and compliance with international chemical safety standards. Our manufacturing facility is equipped to handle large-scale production, supporting both pilot plant requirements and commercial bulk demands.

Storage and Handling

To maintain optimal chemical stability, N-Boc-Glycine Methyl Ester should be stored in a cool, dry environment away from direct sunlight and moisture. Containers must be kept tightly closed when not in use to prevent hydrolysis of the ester group. The recommended storage temperature is between 2°C and 8°C for long-term preservation, although short-term storage at ambient temperature is acceptable under dry conditions. Proper handling procedures include the use of personal protective equipment to minimize exposure during weighing and transfer operations.

Packaging and Logistics

We offer flexible packaging solutions to meet diverse customer needs. The standard packaging configuration is 25 kg per drum, secured with inner liners to ensure product integrity during transit. Customized packaging options are available upon request to accommodate specific logistical requirements. Our global supply chain network ensures timely delivery to major pharmaceutical hubs worldwide, supported by comprehensive documentation for customs clearance and regulatory compliance.