Understanding 4-(Aminomethyl)tetrahydro-2H-pyran: A Key Pharmaceutical Intermediate
Explore the synthesis, applications, and market relevance of a critical building block in modern drug discovery.
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4-(Aminomethyl)tetrahydro-2H-pyran
This compound is a vital fine chemical intermediate, primarily recognized for its role as a reagent in drug discovery. Its chemical structure allows for precise modifications in the development of potent inhibitors, particularly targeting key biological pathways implicated in various diseases.
- Leveraging 4-(Aminomethyl)tetrahydro-2H-pyran synthesis techniques ensures a reliable supply for critical research needs.
- Its application as a reagent in the discovery of CC214-2 highlights its importance in developing orally available, selective inhibitors.
- The compound's role in developing pyrazoloquinolines as PDE10A inhibitors is crucial for advancing treatments for neurological conditions like schizophrenia.
- As a versatile heterocyclic building block, it facilitates complex organic synthesis, enabling the creation of novel chemical entities with therapeutic potential.
Key Advantages Provided
High Purity & Quality
Ensuring high purity (typically ≥98.0%) is paramount for its use in pharmaceutical intermediates, guaranteeing reliable results in drug discovery and synthesis.
Synthetic Versatility
Its reactive amine and ether functionalities make it a versatile building block for a wide range of organic transformations, facilitating the creation of complex molecular architectures.
Therapeutic Target Engagement
The compound's established role in the development of inhibitors for critical targets like mTOR kinase and PDE10A underscores its value in addressing significant unmet medical needs.
Key Applications
Pharmaceutical Synthesis
Used as a key reagent in the synthesis of active pharmaceutical ingredients (APIs), especially those targeting kinases and enzymes involved in disease pathways.
Drug Discovery
Serves as a crucial building block in the discovery process for novel therapeutic agents, aiding in the modification of lead compounds for improved efficacy.
Organic Synthesis
A valuable heterocyclic intermediate for academic and industrial research, enabling the creation of diverse organic molecules with specific functionalities.
Chemical Research
Employed as a chemical reagent for various research applications, contributing to advancements in medicinal chemistry and chemical biology.