High-Purity Phosphoramidite for Advanced Oligonucleotide Synthesis
As a leading manufacturer and supplier in China, we offer N-Acetyl-5'-O-(4,4-dimethoxytrityl)-2'-O-methylcytidine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite (CAS 199593-09-4), a crucial component for synthesizing nuclease-resistant and thermally stable oligonucleotides, driving innovation in therapeutic and diagnostic applications.
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N-Acetyl-5'-O-(4,4-dimethoxytrityl)-2'-O-methylcytidine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite
As a trusted manufacturer in China, we provide a high-quality phosphoramidite engineered for exceptional performance. This reagent is essential for creating modified oligonucleotides with enhanced nuclease resistance and thermal stability. Its reliable supply ensures that researchers and pharmaceutical companies can confidently purchase this key building block for developing advanced nucleic acid therapeutics and diagnostics. Explore our competitive price and purchase options as your preferred supplier.
- Superior Nuclease Resistance: Incorporate 2'-O-methyl modifications to significantly improve oligonucleotide stability against enzymatic degradation, crucial for in vivo applications.
- Enhanced Thermal Stability: Achieve higher binding affinity to target sequences, leading to more robust and effective oligonucleotide probes and therapeutics.
- Automated Synthesis Compatibility: Designed for seamless integration with standard automated DNA/RNA synthesizers, ensuring efficient and reproducible oligonucleotide production.
- High Purity and Quality: Our commitment as a leading manufacturer guarantees a product with stringent quality control, meeting the demands of complex research and pharmaceutical development.
Key Advantages for Your Research and Development
Improved Oligonucleotide Longevity
The 2'-O-methyl modification makes synthetic oligonucleotides highly resistant to degradation by nucleases, extending their in vivo half-life and efficacy for therapeutic applications. Enquire about bulk purchase options from our reliable manufacturer.
Enhanced Target Binding Affinity
Oligonucleotides synthesized with this phosphoramidite exhibit increased thermal stability, enabling stronger and more specific binding to target RNA or DNA sequences. This is vital for accurate diagnostics and effective gene silencing.
Streamlined Synthesis Process
Engineered for compatibility with automated synthesis platforms, this reagent simplifies the production of complex oligonucleotides, allowing researchers to focus on application development rather than complex synthesis protocols.
Versatile Applications in Biotechnology and Beyond
Therapeutic Oligonucleotides
Utilize this phosphoramidite for the synthesis of next-generation antisense oligonucleotides (ASOs), siRNAs, and aptamers, offering improved pharmacokinetic profiles and therapeutic efficacy. Buy high-quality intermediates from our China supplier.
Diagnostic Probes
Develop highly specific and stable nucleic acid probes for applications like PCR, qPCR, and FISH, ensuring sensitive and accurate detection of biomarkers. Get a competitive price quote for your research needs.
Molecular Biology Research
Employ this reagent in fundamental research to study gene function, RNA structure, and develop novel molecular tools. Partner with us as your trusted supplier for innovative reagents.
Custom Oligonucleotide Services
Leverage our expertise as a manufacturer to provide custom synthesis services, integrating this key phosphoramidite into your proprietary oligonucleotide designs. Contact us for a purchase inquiry.