Speciality Chemicals

3,3-Dimethyl-1-(trifluoromethyl)-1,2-benziodoxole

  • CAS No.887144-97-0
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity trifluoromethylation reagent designed for advanced organic synthesis. Ideal for introducing CF3 groups into aromatics and heteroaromatics with excellent stability and reactivity.

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Product Technical Details

Product Overview

3,3-Dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, widely recognized in the scientific community as Togni Reagent II, represents a cornerstone in modern organofluorine chemistry. This hypervalent iodine compound serves as a robust electrophilic trifluoromethylating agent, enabling chemists to introduce trifluoromethyl groups into complex molecular architectures with high precision. Our manufacturing process ensures exceptional purity levels, making it suitable for demanding pharmaceutical research and new material development applications.

As a leading supplier in the fluorochemical sector, we provide this specialized reagent with comprehensive quality documentation. The compound is characterized by its stability under standard storage conditions and its reliable performance in various synthetic transformations. It is particularly valued for its ability to functionalize electron-rich and electron-deficient substrates alike.

Technical Specifications

ParameterSpecification
Chemical Name3,3-Dimethyl-1-(trifluoromethyl)-1,2-benziodoxole
CAS Registry Number887144-97-0
Molecular FormulaC10H10F3IO
Molecular Weight330.09 g/mol
Melting Point75-79 ºC
Purity>98.0% (GC)
AppearanceWhite to off-white powder

Industrial Applications

This reagent is primarily utilized in the synthesis of pharmaceutical intermediates, agrochemicals, and advanced functional materials. The trifluoromethyl group is a critical motif in drug design, often enhancing metabolic stability and lipophilicity. Our product facilitates the following key reactions:

  • Electrophilic trifluoromethylation of aromatic and heteroaromatic compounds.
  • Synthesis of trifluoromethylated ketones and esters.
  • Functionalization of N-heterocycles for medicinal chemistry programs.
  • Development of novel fluorinated polymers and liquid crystals.

Quality and Supply

We maintain a complete fluorochemical technology platform, ensuring consistent supply chains from raw material procurement to final quality control. Each batch is accompanied by a Certificate of Analysis (COA) verifying identity and purity. Our commitment to industrial purity standards supports seamless integration into your manufacturing processes or research workflows.