AM2394: Potent Glucokinase Activator for Metabolic Research and Diabetes Studies
Discover the key to regulating glucose metabolism with AM2394, a leading glucokinase activator.
Get a Quote & SampleProduct Core Value
AM2394
AM2394 is a potent and orally bioavailable glucokinase activator (GKA) with a demonstrated EC50 of 60 nM. This compound significantly enhances the affinity of glucokinase for glucose, approximately tenfold, leading to effective glucose lowering in various animal models. Its good oral bioavailability and moderate cross-species clearance make it an invaluable tool for research into metabolic disorders, particularly type 2 diabetes.
- Explore the potential of AM2394 glucokinase activator in your metabolic research studies.
- Benefit from its potent effect: glucokinase activator EC50 60 nM.
- Utilize its oral bioavailability for convenient administration in preclinical models.
- Investigate AM2394 glucose lowering effects for diabetes treatment development.
Product Advantages
Enhanced Glucose Regulation
AM2394 acts as a glucokinase activator, boosting the enzyme's affinity for glucose. This key mechanism helps in maintaining balanced glucose levels, a critical aspect of diabetes research.
Therapeutic Potential
As an orally bioavailable compound, AM2394 exhibits strong glucose-lowering activity in animal models, highlighting its potential as a therapeutic agent for type 2 diabetes and other metabolic conditions.
Research Versatility
With its well-defined activity and bioavailability, AM2394 serves as an excellent metabolic research compound for in-depth studies on glucose homeostasis and related pathways.
Key Applications
Metabolic Research
Investigate the intricate pathways of glucose metabolism and energy balance using AM2394, a critical diabetes research chemical.
Drug Discovery & Development
AM2394 serves as a valuable intermediate in the discovery of novel antidiabetic drugs and metabolic pathway modulators.
Biochemical Assays
Its precise activity makes AM2394 an ideal tool for developing and validating biochemical assays focused on glucokinase function.
Type 2 Diabetes Studies
Explore the mechanisms behind type 2 diabetes and test novel treatment strategies with this effective GKA, making it a key component for pharmaceutical intermediate suppliers.