Understanding the fundamental chemical properties and synthesis pathways of compounds like 4-Methylthio-2-butanone (CAS 34047-39-7) is crucial for their effective application in industry. This organosulfur compound, essential to the flavor and fragrance sectors, possesses a unique molecular structure that dictates its behavior and utility.

The chemical identity of 4-Methylthio-2-butanone is defined by its formula C5H10OS, with a molecular weight of approximately 118.2 g/mol. Its structure features a ketone group and a methylthio ether group attached to a four-carbon chain. This combination is responsible for its characteristic sensory properties and chemical reactivity. It is classified as a ketone, specifically an aliphatic ketone, with a sulfur-containing substituent.

Key physical properties include its state as a colorless to pale yellow liquid at room temperature. It possesses a relatively high boiling point, typically around 105-107 °C at 55 mmHg, and a flash point of about 162 °F (72.2 °C). Solubility data indicates it is soluble in alcohol but has limited solubility in water, a factor that influences its formulation in various applications. The compound's logarithmic octanol-water partition coefficient (logP) is around 0.646, suggesting a moderate degree of hydrophilicity.

The synthesis of 4-Methylthio-2-butanone often involves the reaction of precursors that introduce both the carbonyl group and the methylthio functionality. Common methods cited in literature include the reaction of methylvinyl ketone with methylmercaptan or its equivalent, or through reactions involving halogenated ketones and thiols. For industrial-scale production, efficient and high-yield synthetic routes are employed to ensure the purity and consistency required for its applications. Ensuring high purity is particularly important for its use as a flavor and fragrance ingredient, where even trace impurities can significantly alter the sensory profile.

NINGBO INNO PHARMCHEM CO.,LTD. specializes in the production of such fine chemicals, adhering to strict manufacturing protocols to achieve the desired purity and yield for 4-Methylthio-2-butanone. Our expertise in chemical synthesis allows us to reliably supply this compound, supporting the innovation and product development needs of our clients across various industries. By understanding the chemical backbone of this ingredient, manufacturers can better leverage its potential in their product formulations.