The fight against cancer is heavily reliant on sophisticated pharmaceutical interventions, with taxane chemotherapy agents like paclitaxel and docetaxel playing a pivotal role. Central to the efficient production of these life-saving drugs is the intermediate compound known as 10-Deacetylbaccatin III (CAS 32981-86-5). As a leading chemical supplier, understanding and providing this vital precursor is at the core of our mission.

The Molecular Significance of 10-Deacetylbaccatin III

10-Deacetylbaccatin III is a complex natural product, extracted from the bark and needles of yew trees. Its intricate diterpenoid structure serves as the foundational scaffold for the taxane class of anti-cancer drugs. Typically appearing as a pure white crystalline powder, its chemical formula is C29H36O10, with a molecular weight of 544.59 g/mol. The high purity, often exceeding 99% when analyzed by HPLC, is essential for its successful conversion into therapeutic agents. This compound's availability is directly linked to the feasibility of synthesizing paclitaxel and docetaxel, making it a sought-after pharmaceutical intermediate.

From Precursor to Therapy: The Synthesis Pathway

The transformation of 10-Deacetylbaccatin III into paclitaxel and docetaxel involves complex multi-step chemical processes. These synthetic routes leverage the inherent structure of 10-Deacetylbaccatin III to introduce specific side chains that confer the cytotoxic activity. Without a consistent and high-quality supply of this precursor, the production of these crucial chemotherapies would be severely hampered. This underscores the importance of partnering with reliable manufacturers of 10-Deacetylbaccatin III.

Why Partner with a Reputable Supplier?

For research institutions and pharmaceutical companies, sourcing 10-Deacetylbaccatin III requires diligence. Key considerations when you look to buy 10-Deacetylbaccatin III include:

  • Guaranteed Purity and Quality: Ensuring the intermediate meets stringent assay requirements is critical for reproducible results and drug efficacy.
  • Supply Chain Reliability: A consistent and stable supply is necessary for ongoing research and commercial production.
  • Technical Support and Documentation: Access to Certificates of Analysis (COA) and technical data is vital for regulatory compliance and research validation.
  • Competitive Pricing: Securing this intermediate at a reasonable cost is important for managing project budgets.

As a leading 10-Deacetylbaccatin III supplier in China, we are committed to providing the highest quality product to support advancements in cancer treatment. Our expertise in natural product chemistry and pharmaceutical intermediate synthesis ensures that your R&D and production needs are met with excellence.