In the dynamic landscape of scientific research, access to high-quality chemicals is fundamental. Fumagillin, identified by its CAS number 23110-15-8, is a compound that has established itself as a critical research chemical due to its significant biological activities, notably its anti-angiogenic and antiprotozoal effects. For researchers and procurement specialists, understanding the properties of Fumagillin and how to efficiently buy Fumagillin from reliable sources is essential for advancing their work.

Fumagillin: Properties and Scientific Utility

Fumagillin, with the chemical formula C26H34O7 and a molecular weight of 458.54 g/mol, is typically supplied as a white powder. Its principal scientific interest lies in its potent inhibition of methionine aminopeptidase-2 (MetAP-2). This enzyme is crucial for cellular processes, and its inhibition by Fumagillin leads to reduced endothelial cell proliferation and migration, thereby inhibiting angiogenesis – the formation of new blood vessels. This makes Fumagillin a vital tool in research related to cancer, wound healing, and other vascular-related conditions.

Researchers seeking to leverage Fumagillin in their studies often prioritize high purity, commonly specified as ≥90% by HPLC. This ensures the accuracy and reliability of experimental results. When you need to purchase Fumagillin, focusing on suppliers who guarantee these specifications is paramount.

Key Applications of Fumagillin in Research

Fumagillin finds application in several scientific disciplines:

  • Cancer Research: Its anti-angiogenic action is extensively studied in the context of inhibiting tumor growth and metastasis.
  • Vascular Biology: It's used to probe the intricate mechanisms of angiogenesis and endothelial cell function.
  • Biochemical Studies: As a specific enzyme inhibitor, it aids in understanding MetAP-2's role in cellular metabolism and protein synthesis.
  • Parasitology: Its efficacy against certain protozoan parasites also makes it relevant for infectious disease research.

When inquiring about the 'methionine aminopeptidase-2 inhibitor price', it's important to get detailed quotes based on the required purity and quantity.

Efficient Sourcing of Fumagillin (CAS 23110-15-8)

To procure Fumagillin effectively, especially for bulk needs, consider partnering with established chemical manufacturers and suppliers. A search for a 'Fumagillin supplier China' can often yield competitive pricing and a robust supply chain. When you choose a supplier, look for:

  • Quality Documentation: Ensure availability of Certificates of Analysis (CoA) and Safety Data Sheets (SDS).
  • Purity Guarantees: Confirm the product meets or exceeds specified purity levels.
  • Bulk Order Capabilities: If you intend to buy Fumagillin bulk quantity, direct engagement with manufacturers like NINGBO INNO PHARMCHEM CO.,LTD. is recommended for better terms and consistent supply.
  • Technical Support: Access to expert advice can be invaluable for optimizing its use.

By leveraging these sourcing strategies, researchers and institutions can ensure they have a reliable and high-quality supply of Fumagillin, thereby facilitating continued scientific progress.