In the dynamic field of peptide synthesis, precision and accuracy are paramount. Researchers and developers are constantly seeking advanced reagents that can offer greater control and insight into their work. One such class of indispensable tools are isotopically labeled amino acids, and among them, Fmoc-Asp(OtBu)-OH (13C4,15N) stands out for its significant contributions to sophisticated analytical techniques.

Fmoc-Asp(OtBu)-OH (13C4,15N), identified by its CAS number 1217468-27-3, is a derivative of aspartic acid where specific carbon atoms and the nitrogen atom are enriched with stable isotopes. This enrichment is not merely a chemical modification; it's a gateway to advanced analytical methodologies, particularly in quantitative mass spectrometry. For professionals looking to buy this specialized chemical, understanding its role is key.

The primary application of Fmoc-Asp(OtBu)-OH (13C4,15N) lies in Solid-Phase Peptide Synthesis (SPPS) utilizing Fmoc (9-fluorenylmethyloxycarbonyl) chemistry. When incorporated into a growing peptide chain, the isotopic label acts as an internal standard. This allows for highly accurate quantification of the target peptide, even in complex biological matrices. This capability is invaluable for pharmaceutical companies developing peptide-based drugs, where precise measurement of drug concentration, metabolism, and pharmacokinetics is crucial for regulatory approval and clinical success. Sourcing these critical building blocks from a reliable manufacturer in China ensures consistent quality and availability.

Beyond quantitative analysis, these labeled compounds are also instrumental in metabolic tracing studies. By tracking the labeled atoms through biological pathways, scientists can gain deeper insights into how peptides are synthesized, processed, and degraded within living organisms. This is particularly important in areas like proteomics, systems biology, and understanding disease mechanisms. Companies seeking to purchase such specialized reagents can benefit from competitive pricing and efficient supply chains offered by established suppliers.

The purity and isotopic enrichment of labeled amino acids are critical factors for their effectiveness. Reputable chemical manufacturers invest heavily in quality control to ensure that their products meet the stringent requirements of the pharmaceutical and biotechnology sectors. When you buy Fmoc-Asp(OtBu)-OH (13C4,15N), you are investing in the integrity of your research. The use of these advanced chemical intermediates is rapidly becoming standard practice for cutting-edge research, making them an essential part of any advanced synthesis laboratory’s toolkit.

In conclusion, Fmoc-Asp(OtBu)-OH (13C4,15N) represents a significant advancement in the field of peptide synthesis and analysis. Its ability to enhance quantitative accuracy and enable detailed metabolic studies makes it a highly sought-after reagent. For procurement professionals and research scientists, identifying a dependable supplier offering competitive prices for high-quality, isotopically labeled amino acids like this is a strategic imperative for driving innovation in drug discovery and development.