In the intricate field of neuroscience, understanding the molecular mechanisms behind complex conditions like depression is paramount. Researchers actively seek reliable tools to probe these pathways, and peptides like PE 22-28 have emerged as vital components in this quest. As a leading manufacturer and supplier of specialized research chemicals, we are committed to providing scientists with the high-quality materials they need to push the boundaries of their work.

PE 22-28, identified by its CAS number 1801959-12-5, is a precisely synthesized 7-amino acid peptide. Its significance lies in its potent inhibitory action on TREK-1 channels, a class of ion channels implicated in various neurological functions, including mood regulation. With an impressive IC50 value of 0.12 nM, PE 22-28 offers researchers a highly specific and effective agent for studying the role of TREK-1 in physiological and pathological processes.

The therapeutic potential of modulating TREK-1 channels has garnered significant attention, particularly in the context of depression. Studies, including those referenced in scientific literature, suggest that PE 22-28 exhibits antidepressant properties. This makes it an invaluable tool for scientists investigating novel treatment strategies for mood disorders. By inhibiting TREK-1, researchers can explore pathways that may lead to improved outcomes for patients suffering from depression.

Beyond its antidepressant applications, PE 22-28 has also demonstrated promise in other areas of neurological research. Its ability to reduce apoptotic cell death, particularly in beta cells, and to increase hippocampal neurogenesis highlights its potential neuroprotective capabilities. These findings are crucial for understanding recovery mechanisms following ischemic events and for developing interventions to mitigate stroke-induced cognitive and motor impairments. Purchasing PE 22-28 from a reputable supplier ensures that you receive a product with the purity and consistency required for such sensitive in vivo and in vitro studies.

For procurement, sourcing PE 22-28 as a scientific reagent from a reliable manufacturer is key. We pride ourselves on being a trusted supplier, offering this peptide with a purity of over 99%. Whether you are looking to buy PE 22-28 for initial research, dose-response studies, or developing new peptide-based therapies, our streamlined purchasing process and competitive pricing ensure accessibility. We understand the critical nature of supply chain stability for research institutions and pharmaceutical companies, and we are dedicated to meeting these demands. Explore the benefits of purchasing PE 22-28 in China, ensuring both quality and cost-effectiveness for your laboratory.

In conclusion, PE 22-28 stands as a critical research peptide for those delving into the complexities of neurological function and dysfunction. Its potent TREK-1 inhibitory activity and demonstrated in vivo effects make it an indispensable asset for depression research, neuroprotection studies, and the broader field of neuropharmacology. We invite researchers to inquire about pricing and availability, and to secure this vital scientific reagent to advance their groundbreaking work.