In the competitive landscape of chemical manufacturing and research, the reliable procurement of intermediates like 2-Bromo-4'-chloroacetophenone (CAS: 536-38-9) is fundamental to success. This compound, also known as 4-Chlorophenacyl bromide, is a critical component in numerous synthetic pathways, particularly within the pharmaceutical sector. This guide aims to equip procurement managers and R&D scientists with the knowledge to effectively buy this essential chemical.

Understanding the Chemical Profile: 2-Bromo-4'-chloroacetophenone

2-Bromo-4'-chloroacetophenone (C8H6BrClO) is an organic compound valued for its chemical properties, including its specific reactivity due to the alpha-bromine atom and the presence of a chlorine substituent on the phenyl ring. It typically exists as a white to light yellow solid, with a melting point ranging from 93-99°C. High purity, often specified as ≥99.0%, is crucial for its applications, ensuring predictable reaction outcomes and the integrity of downstream products. Its molecular weight is 233.49 g/mol.

Why is Quality Crucial?

For pharmaceutical intermediates, purity is not just a specification; it's a guarantee of safety and efficacy. Impurities in 2-Bromo-4'-chloroacetophenone can lead to unwanted side reactions, reduced yields, and, critically, affect the safety profile of the final pharmaceutical product. Therefore, buyers should always prioritize suppliers who provide stringent quality control and detailed Certificates of Analysis (COA) confirming purity and identifying any trace contaminants. Manufacturers often list purity levels such as ≥99.0% or 99.5%.

Navigating Pricing and Procurement

The price of 2-Bromo-4'-chloroacetophenone can vary significantly based on purity, quantity, and supplier. When looking to purchase, it's advisable to obtain quotes from multiple manufacturers and distributors. Key considerations for pricing include:

  • Volume Discounts: Bulk purchases generally offer lower per-unit costs.
  • Purity Specifications: Higher purity grades will naturally command higher prices.
  • Supplier's Geographic Location: Manufacturers in China often offer competitive pricing due to production efficiencies.
  • Logistics and Shipping: Factor in the cost of transportation and any import duties.

For any serious inquiry, requesting a formal quote is the best approach. This ensures clarity on exact product specifications, pricing, and delivery timelines.

Finding Reliable Suppliers

Identifying trustworthy suppliers of 2-Bromo-4'-chloroacetophenone involves due diligence. Look for suppliers who:

  • Clearly state their manufacturing origin (e.g., China).
  • Provide comprehensive product documentation (SDS, COA).
  • Demonstrate a strong understanding of their product's applications.
  • Offer clear communication channels for inquiries and technical support.
  • Have a history of reliable delivery and positive customer feedback.

By focusing on these aspects, businesses can ensure they are sourcing a high-quality chemical intermediate that meets their project's requirements, thereby optimizing their R&D efforts and manufacturing processes. Secure your supply of this vital compound by engaging with reputable manufacturers today.