In the realm of advanced chemical synthesis, the precision and versatility of building blocks play a crucial role in driving innovation. Azido-PEG4-carboxylic acid (CAS: 1257063-35-6) stands out as a prime example of such a versatile intermediate, widely utilized in sophisticated chemical synthesis and bioconjugation strategies. As a dedicated chemical manufacturer and supplier from China, we offer this high-purity compound to researchers and industries worldwide, facilitating groundbreaking advancements.

Understanding the Chemical Versatility of Azido-PEG4-carboxylic Acid

Azido-PEG4-carboxylic acid is characterized by its unique bifunctional nature. It incorporates a terminal azide group (-N3) and a terminal carboxylic acid group (-COOH) connected by a four-unit polyethylene glycol (PEG) chain. This specific arrangement provides chemists with dual reactive handles, enabling a broad spectrum of synthetic transformations.

The azide moiety is central to the utility of this compound in 'click chemistry'. This highly efficient and selective reaction class, particularly the copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC) or strain-promoted azide-alkyne cycloaddition (SPAAC), allows for the formation of stable triazole linkages under mild conditions. This makes Azido-PEG4-carboxylic acid an ideal reagent for conjugating diverse molecules, including biomolecules, polymers, and surfaces, with remarkable specificity. Researchers actively seeking to buy such functionalized PEG derivatives often turn to reliable suppliers in China for competitive pricing and availability.

Complementing the azide group, the carboxylic acid terminus can be readily activated and coupled with amines to form robust amide bonds. This dual reactivity allows for sequential or orthogonal conjugation strategies, offering significant flexibility in designing complex molecular architectures. Whether used in the synthesis of targeted drug conjugates, the modification of nanoparticles, or the creation of novel functional materials, Azido-PEG4-carboxylic acid proves to be an indispensable intermediate.

Sourcing from a Premier Chinese Manufacturer

As a leading producer of fine chemical intermediates, we are committed to providing products that meet the highest standards of purity and quality. Our Azido-PEG4-carboxylic acid is guaranteed to have a purity of 97% minimum, ensuring reliable performance in your demanding applications. We understand the importance of consistent supply for R&D pipelines and manufacturing. Therefore, we strive to maintain robust production capabilities and efficient delivery systems. For procurement professionals, investigating the CAS 1257063-35-6 chemical intermediate price through direct inquiry with a reputable manufacturer like us ensures the best value.

Our role extends beyond merely supplying chemicals. We aim to be a partner in your scientific journey, offering support and flexibility to meet your specific needs. Whether you require small research quantities or bulk orders for commercial production, our team is equipped to assist. Companies looking to purchase advanced intermediates for novel applications in areas like drug delivery, diagnostics, or materials science can rely on our expertise and product portfolio.

Key Applications Driving Chemical Innovation

  • Bioconjugation: Essential for creating antibody-drug conjugates (ADCs), protein-ligand conjugates, and labeling biomolecules with fluorophores or other tags.
  • Drug Delivery: Used in PEGylation to improve the solubility, stability, and pharmacokinetic profiles of therapeutic agents.
  • Materials Science: Enables surface functionalization and the creation of smart materials with tailored properties.
  • PROTAC Synthesis: Serves as a linker component in the development of targeted protein degradation agents.

The strategic use of Azido-PEG4-carboxylic acid in advanced chemical synthesis highlights its importance in modern research. By choosing a reliable Chinese manufacturer and supplier, you ensure access to a high-quality, versatile intermediate that can accelerate your project timelines and drive successful outcomes. We encourage you to contact us to learn more about our products and how we can support your specific research and manufacturing needs.