In the intricate world of pharmaceutical development and peptide synthesis, the quality of raw materials is paramount. For R&D scientists and procurement managers, identifying and securing a reliable source for specialized intermediates like N-Acetyl-L-aspartic acid 4-tert-butyl ester (CAS 117833-18-8) is a critical step. This amino acid derivative, often referred to as ac-asp(otbu)-oh, plays a vital role as a building block in creating complex molecules. Understanding its specifications and the benefits of partnering with a reputable manufacturer is key to successful outcomes.

Why High Purity Matters for ac-asp(otbu)-oh

N-Acetyl-L-aspartic acid 4-tert-butyl ester, with its specific chemical structure (C10H17NO5), is valued for its protected amino and carboxyl groups. When you buy this compound for pharmaceutical intermediate applications, particularly in API synthesis or complex peptide chains, a high purity level (typically ≥98%) is non-negotiable. Impurities can lead to side reactions, reduced yields, and, crucially, compromise the safety and efficacy of the final pharmaceutical product. Therefore, choosing a supplier that guarantees stringent quality control is essential. If you are looking to buy this intermediate, prioritize suppliers who provide comprehensive Certificates of Analysis (CoA).

Sourcing Strategies: Finding a Trusted Manufacturer in China

China has emerged as a global hub for chemical manufacturing, offering competitive pricing and a vast array of specialized compounds. For N-Acetyl-L-aspartic acid 4-tert-butyl ester, identifying a reliable manufacturer involves looking beyond just the lowest price. Key considerations include:

  • Production Capabilities: Does the manufacturer have established processes for producing this specific compound with consistent quality?
  • Quality Assurance: What measures are in place to ensure purity and meet industry standards? Look for ISO certifications or similar quality management systems.
  • Technical Support: Can they provide technical data, support, and answer specific questions about the product's application?
  • Customer Reviews and Reputation: What do other buyers say about their experience with the supplier's products and service?

When you search for a supplier of N-Acetyl-L-aspartic acid 4-tert-butyl ester, engaging with manufacturers directly can often lead to better pricing and a deeper understanding of their capabilities. Procurement managers should always request quotes and samples to perform their due diligence.

Key Applications and Why Purchase This Derivative?

The primary use of N-Acetyl-L-aspartic acid 4-tert-butyl ester is as a protected amino acid in peptide synthesis. The tert-butyl ester provides a readily cleavable protecting group for the aspartic acid side chain carboxyl, while the N-acetyl group protects the amino terminus. This dual protection is critical for step-wise amino acid addition in peptide chains. For those involved in drug discovery, especially in developing peptide-based therapeutics, procuring this intermediate is a fundamental step. Its role extends to general organic synthesis as a chiral building block, allowing for the construction of complex molecular architectures with stereochemical control.

Conclusion: Invest in Quality for Your Research

For R&D scientists and procurement professionals in the pharmaceutical and biotechnology sectors, understanding the importance of high-purity N-Acetyl-L-aspartic acid 4-tert-butyl ester is crucial. By partnering with a reputable manufacturer and supplier, you ensure the quality and consistency needed for successful synthesis. When you are ready to buy, consider the detailed specifications, manufacturing expertise, and reliable supply chain offered by leading producers. Prioritizing a quality supplier will directly impact the efficiency and success of your research and development projects.