In the specialized field of chemical manufacturing, certain compounds serve as fundamental building blocks that enable significant advancements in various industries. (R)-(+)-3-Butyn-2-ol, known by its CAS number 42969-65-3, is such a compound. This chiral alcohol, also referred to as (2R)-but-3-yn-2-ol or (R)-(+)-3-Butyn-2-ol, is a colorless transparent liquid celebrated for its role in sophisticated organic synthesis and as a crucial intermediate in the pharmaceutical sector.

The molecular structure of (R)-(+)-3-Butyn-2-ol, with its characteristic alkyne moiety and chiral center, provides a unique reactive profile. Its molecular formula is C4H6O, and it has a molecular weight of 70.090. The compound is typically manufactured to a high purity standard, with an assay of ≥98.0%, making it ideal for applications where precision and reliability are paramount. The precise stereochemistry of this molecule is vital for stereospecific reactions, which are foundational in the synthesis of many pharmaceutical agents.

The foremost application of (R)-(+)-3-Butyn-2-ol is its critical role as an intermediate in the synthesis of Vorapaxar Sulfate (CAS: 705260-08-8). Vorapaxar Sulfate is a key component in antiplatelet therapy, used to reduce the risk of thrombotic cardiovascular events. The production of this pharmaceutical necessitates intermediates that meet exacting standards, and (R)-(+)-3-Butyn-2-ol reliably fulfills this requirement. Consequently, the demand for high-quality (R)-(+)-3-Butyn-2-ol from reputable suppliers, including many based in China, remains robust.

Beyond its pharmaceutical significance, (R)-(+)-3-Butyn-2-ol finds utility in broader organic synthesis due to its versatile reactivity. Its physical properties, such as a boiling point of 108-111 ºC and a flash point of 10 ºC, dictate its handling and storage protocols, requiring cool and well-ventilated conditions. Manufacturers like NINGBO INNO PHARMCHEM CO.,LTD. ensure that these critical aspects are managed to maintain product integrity and safety. For companies looking to buy (R)-(+)-3-Butyn-2-ol, understanding its chemical versatility and the importance of sourcing from reliable manufacturers is key.

As the pharmaceutical industry continues to innovate, the demand for essential chiral intermediates like (R)-(+)-3-Butyn-2-ol is poised to grow. The robust manufacturing capabilities in China provide a stable and high-quality supply, supporting global efforts in drug development and chemical synthesis.