At NINGBO INNO PHARMCHEM CO.,LTD., we often advise clients on selecting the most appropriate chemical intermediates for their diverse needs. Among these, emulsifiers like Polysorbate 80 (Tween 80) and Sorbitan Monooleate (Span 80) are frequently discussed. While both are surfactants used to stabilize emulsions, their distinct chemical structures and Hydrophilic-Lipophilic Balance (HLB) values dictate their suitability for different applications. Understanding these nuances is key to successful formulation.

Polysorbate 80, or Tween 80, is characterized by its polyoxyethylene chains attached to a sorbitan monooleate backbone. These hydrophilic chains give it a high HLB value, typically around 15. This high HLB signifies its preference for water and makes it an excellent choice for creating oil-in-water (O/W) emulsions. These are systems where oil droplets are dispersed within a continuous water phase, common in products like salad dressings, lotions, and many pharmaceutical suspensions. Exploring the tween 80 surfactant functions reveals its versatility in O/W systems.

In contrast, Span 80 is a sorbitan ester without the polyoxyethylene chains. This makes it more hydrophobic, resulting in a low HLB value, typically around 4.3. Its lipophilic nature makes it ideal for stabilizing water-in-oil (W/O) emulsions, where water droplets are dispersed within a continuous oil phase. These are found in products like butter, margarine, and certain heavy creams or ointments. The selection process often hinges on detailed polysorbate 80 properties versus Span 80 properties.

The choice between Tween 80 and Span 80 often depends on the desired emulsion type. If your goal is to create a stable product where water is the continuous phase and oil is dispersed, Tween 80 is the preferred choice. Conversely, if your formulation requires oil to be the continuous phase with water dispersed within it, Span 80 is more suitable. Manufacturers often buy Polysorbate 80 for its broad utility in O/W systems, while Span 80 is favored for its role in W/O systems.

As a leading polysorbate 80 supplier, NINGBO INNO PHARMCHEM CO.,LTD. offers both high-quality Polysorbate 80 and related emulsifiers. By understanding the chemistry and the specific tween 80 price point, formulators can make informed decisions to optimize their products. Whether you need an O/W or W/O emulsifier, our range of ingredients is designed to meet your formulation challenges.