(1R,2R)-Cyclohexane-1,2-diyldimethanol
- CAS No.65376-05-8
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High purity (1R,2R)-Cyclohexane-1,2-diyldimethanol CAS 65376-05-8. A premium chiral intermediate essential for the synthesis of advanced pharmaceutical agents like Lurasidone.
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Product Overview
(1R,2R)-Cyclohexane-1,2-diyldimethanol is a highly specialized chiral building block utilized extensively in the pharmaceutical industry. As a critical intermediate, this compound plays a pivotal role in the stereoselective synthesis of complex therapeutic agents. Our manufacturing process ensures exceptional enantiomeric purity, making it an ideal candidate for demanding organic synthesis routes where stereochemistry dictates biological activity. We adhere to strict quality control protocols to deliver material that meets rigorous international standards for pharmaceutical production.
This cyclohexane derivative features a trans-configuration that provides unique structural rigidity and reactivity. Such characteristics are indispensable when constructing molecular frameworks for next-generation medications. Our facility is equipped to handle large-scale production while maintaining the integrity of the chiral centers, ensuring consistent batch-to-batch performance for our global partners.
Technical Specifications
Quality is the cornerstone of our chemical supply chain. Each batch undergoes comprehensive analysis to verify identity, purity, and impurity profiles. The following table outlines the key physical and chemical parameters guaranteed for this product.
| Items of Analysis | Standard of Analysis | Test Results |
|---|---|---|
| Appearance | Off-white to white powder | Conform |
| Melting point | 60-65℃ | 60.5-63℃ |
| Acid impurity | ≤0.2% | NA |
| Maximum single impurity | ≤0.5% | 0.38% |
| Total Impurities | ≤2.0% | 0.70% |
| Enantiomeric impurity | ≤0.5% | 0.34% |
| Water | ≤0.5% | 0.42% |
| Purity | ≥98.0% | 99.30% |
| Conclusion | Conforms to Factory Standard | |
Industrial Applications
The primary application of (1R,2R)-Cyclohexane-1,2-diyldimethanol lies in the synthesis of advanced pharmaceutical intermediates. It is notably used in the production pathway of Lurasidone, an atypical antipsychotic medication. The high enantiomeric excess provided by our material ensures that the final drug product meets stringent regulatory requirements for safety and efficacy. Beyond this specific application, the compound serves as a versatile ligand or precursor in various asymmetric catalysis reactions.
Chemists value this building block for its stability and predictable reactivity during multi-step synthesis. Whether utilized in research and development or scaled for commercial manufacturing, our product supports the creation of novel therapeutic solutions. We work closely with clients to optimize supply chains for continuous production needs.
Storage and Handling
To maintain optimal quality, this product should be stored in a cool, ventilated environment away from direct sunlight and moisture. Proper packaging ensures protection during transit. We offer flexible packing options, including 25 kg drums, and can customize packaging according to specific customer requirements. Safety data sheets and certificates of analysis are provided with every shipment to facilitate compliant handling and regulatory documentation.
