Intermediates

(2R,3R)-Diisopropyl 2,3-Dihydroxysuccinate

  • CAS No.2217-15-4
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity chiral intermediate essential for pharmaceutical synthesis. Manufactured under strict quality controls with comprehensive COA support.

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Product Technical Details

Product Overview

Welcome to our premium supply of (2R,3R)-Diisopropyl 2,3-dihydroxysuccinate, a critical chiral building block designed for advanced pharmaceutical manufacturing. This specialized ester serves as a fundamental component in the stereoselective synthesis of complex active pharmaceutical ingredients. Our facility ensures that every batch meets rigorous international standards, providing reliability for large-scale production needs.

As a key intermediate, this compound offers exceptional stability and reactivity profiles required for multi-step organic synthesis. The specific stereochemistry at the 2R and 3R positions is meticulously maintained throughout our manufacturing process, ensuring high optical purity for downstream applications. This level of precision is vital for producing effective therapeutic agents where chirality dictates biological activity.

Key Specifications

ParameterSpecification
CAS Number2217-15-4
Molecular FormulaC10H18O6
Molecular Weight234.246 g/mol
AppearanceColorless oil liquid
Assay (GC)≥98.0%
Specific Rotation+16° to +18°
Boiling Point273-275 °C
Density1.114 g/cm³

Industrial Applications

This compound is primarily utilized as a strategic intermediate in the synthesis of immunosuppressant APIs and other complex pharmaceutical agents. Its role involves facilitating the construction of specific chiral centers that are difficult to achieve through racemic synthesis. By using our high-purity grade material, manufacturers can optimize their yield and reduce purification steps in their final drug substance production.

Beyond pharmaceuticals, this diester finds applications in fine chemical synthesis where chiral auxiliaries are required. The isopropyl groups provide steric hindrance that can be leveraged to control reaction pathways, making it a versatile tool for process chemists developing new synthetic routes. Our technical team supports clients in integrating this material into their existing workflows seamlessly.

Quality Assurance and Logistics

Quality is the cornerstone of our operation. Each production lot undergoes comprehensive testing using gas chromatography and polarimetry to verify assay and optical rotation. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring full traceability and compliance with your internal quality systems. Our manufacturing processes are aligned with GMP standards to support regulated industry requirements.

We offer flexible packaging solutions, typically supplying in 200 kg drums, though custom packaging is available upon request to suit specific logistical needs. Storage recommendations include keeping the material in a cool, ventilated area away from direct sunlight and moisture to maintain stability. Our global supply chain ensures timely delivery to support continuous manufacturing operations worldwide.