Intermediates

(2S)-Propane-1,2-Diamine Dihydrochloride

  • CAS No.19777-66-3
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

Premium grade (2S)-propane-1,2-diamine dihydrochloride designed for pharmaceutical synthesis. High purity assurance with global logistics support.

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Product Technical Details

Product Overview

(2S)-Propane-1,2-diamine dihydrochloride is a highly specialized chiral intermediate essential for the synthesis of advanced pharmaceutical compounds. As a key building block in medicinal chemistry, this compound offers exceptional stereochemical integrity, making it indispensable for producing enantiomerically pure active pharmaceutical ingredients. Our manufacturing process ensures consistent quality and reliability for large-scale industrial applications.

This chemical substance is characterized by its stable dihydrochloride salt form, which enhances handling safety and solubility during synthetic procedures. The compound serves as a critical precursor in the production of cardioprotective agents and other therapeutic molecules requiring precise chiral configuration. We adhere to strict quality control protocols to meet international pharmaceutical standards.

Technical Specifications

ParameterValue
CAS Number19777-66-3
Molecular FormulaC3H12Cl2N2
Molecular Weight147.047 g/mol
AppearanceLight yellow powder
Assay≥99.0%
Melting Point227-229°C
Boiling Point215.8°C at 760 mmHg
Flash Point84.3°C

Industrial Applications

The primary application of (2S)-propane-1,2-diamine dihydrochloride lies in the synthesis of complex pharmaceutical intermediates. It is notably utilized in the manufacturing process of Dexrazoxane and its hydrochloride salt, which are vital components in oncology support care. The chiral purity of this diamine derivative ensures the final drug product meets rigorous efficacy and safety profiles required by regulatory bodies.

Beyond oncology support, this compound finds utility in various organic synthesis routes where chiral diamines are required. Researchers and process chemists value this material for its reactivity and stability under standard laboratory and plant conditions. Our supply chain supports both pilot-scale research and commercial production needs.

Quality Assurance and Storage

We maintain a comprehensive quality management system to guarantee product consistency. Every batch undergoes thorough analytical testing, including HPLC and chiral chromatography, to verify purity and stereochemical composition. A Certificate of Analysis (COA) is provided with each shipment to document compliance with specifications.

  • Packaged in 25 kg drums for secure transport.
  • Custom packaging solutions available upon request.
  • Stored in a cool, ventilated environment to maintain stability.
  • Protected from moisture and direct sunlight during warehousing.

Our global logistics network ensures timely delivery while maintaining product integrity throughout the supply chain. We are committed to supporting our partners with reliable supply, competitive bulk pricing, and technical expertise for process optimization.