(R)-Valine Dane Salt

Product Overview

(R)-Valine Dane Salt, identified by CAS number 134841-35-3, is a specialized chiral pharmaceutical intermediate designed for high-level organic synthesis. This potassium salt derivative plays an indispensable role in the manufacturing of advanced veterinary antibiotics, specifically within the pleuromutilin class. Our facility produces this compound under strict quality control protocols to ensure consistent stereochemical integrity and chemical purity, meeting the rigorous demands of modern pharmaceutical manufacturing.

As a key building block, this substance provides the necessary chiral foundation for complex molecular assembly. The precise configuration of the valine moiety is critical for the biological activity of the final therapeutic product. We understand that any deviation in optical purity can significantly impact downstream synthesis efficiency and final drug efficacy. Therefore, our production processes are optimized to maintain exceptional enantiomeric excess and minimize impurities.

Chemical Properties and Structure

Chemically known as Potassium (2R)-2-[(4-methoxy-4-oxo-2-buten-2-yl)amino]-3-methylbutanoate, this compound features a specific potassium salt formation that enhances its stability and solubility during reaction phases. The molecular formula C10H16NO4K reflects its structured composition, with a molecular weight of approximately 253.34 g/mol. The presence of the methoxy and oxo functional groups allows for versatile reactivity in coupling reactions.

The physical appearance is typically a fine white powder, indicating high levels of refinement. While specific physical constants such as boiling point or refractive index may vary based on specific crystalline forms, the primary focus for industrial users is on assay purity and chiral stability. Our batch testing ensures that every lot meets the specified purity threshold of ≥98%, verified through high-performance liquid chromatography (HPLC) and nuclear magnetic resonance (NMR) spectroscopy.

Industrial Applications

The primary application of (R)-Valine Dane Salt is as a crucial intermediate in the total synthesis of Valnemulin (CAS 101312-92-9). Valnemulin is a potent semi-synthetic antibiotic used extensively in veterinary medicine to treat respiratory and digestive infections in livestock. The efficiency of the Valnemulin production line relies heavily on the quality of this chiral precursor. By utilizing our high-grade intermediate, manufacturers can achieve higher yields and reduce waste in their synthesis routes.

Beyond Valnemulin, this chiral valine derivative may serve as a valuable building block for other pharmaceutical research projects requiring stereoselective amino acid components. Its compatibility with various organic synthesis conditions makes it a flexible tool for medicinal chemists developing new therapeutic agents. We support both large-scale commercial production and smaller-scale research and development initiatives.

Quality Assurance and Storage

Quality assurance is paramount in our manufacturing process. Each batch undergoes comprehensive testing before release. We provide a Certificate of Analysis (COA) with every shipment, detailing purity levels, residual solvents, and heavy metal content. Our facilities adhere to international safety and quality standards, ensuring that the product remains stable during transit and storage.

For optimal preservation, this product should be stored in a cool, dry environment, ideally in a refrigerator. Containers must be tightly closed to prevent exposure to moisture, which could affect the salt stability. Additionally, protection from strong light and heat sources is recommended to maintain chemical integrity over extended periods. We offer flexible packaging options, including 25kg cardboard drums, or custom packaging according to specific customer requirements to ensure safe global delivery.