Intermediates

(S)-3-(1-Amino-ethyl)-phenol

  • CAS No.123982-81-0
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity chiral intermediate essential for Rivastigmine synthesis, available in bulk with comprehensive quality documentation.

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Product Technical Details

Product Overview

(S)-3-(1-Amino-ethyl)-phenol is a highly specialized chiral intermediate utilized extensively in the pharmaceutical industry. As a critical building block, this compound plays a pivotal role in the synthesis of advanced neurological therapeutics, specifically serving as a key precursor in the manufacturing process of Rivastigmine. Our facility ensures that every batch meets rigorous international standards, providing pharmaceutical manufacturers with a reliable source of high-quality raw materials for drug development and production.

The stereochemical integrity of this molecule is paramount for its biological activity in downstream applications. We employ advanced chiral resolution techniques to guarantee the specific (S)-enantiomeric configuration required for effective API synthesis. This commitment to precision ensures that our clients can maintain consistent quality in their final pharmaceutical formulations without compromising on efficacy or safety profiles.

Technical Specifications

Our production process is designed to maximize yield while maintaining exceptional purity levels. The physical and chemical properties are strictly monitored throughout the manufacturing cycle. Below are the detailed specifications that define the quality of our (S)-3-(1-Amino-ethyl)-phenol supply.

ParameterSpecification
CAS Number123982-81-0
Molecular FormulaC8H11NO
Molecular Weight137.18 g/mol
AppearanceWhite or light brown crystalline powder
Purity≥97.0%
Density1.096 g/cm3
Boiling Point266.3°C at 760 mmHg
Flash Point114.9°C
Refractive Index1.572

Industrial Applications

This chemical intermediate is primarily designated for the synthesis of Rivastigmine and its tartrate salt, which are widely recognized acetylcholinesterase inhibitors used in the management of Alzheimer's disease. The high purity of our product ensures minimal impurity carry-over into the final active pharmaceutical ingredient, facilitating smoother regulatory approval processes and reducing downstream purification costs.

Beyond its primary application, this compound serves as a valuable chiral building block for various organic synthesis routes requiring a specific phenolic amine structure. Research and development teams utilize this material to explore new neurological therapeutics and optimize existing manufacturing processes. Our technical team provides comprehensive support to help clients integrate this intermediate into their specific synthesis routes effectively.

Quality Assurance and Packaging

Quality control is the cornerstone of our operation. Each production batch undergoes stringent testing using HPLC and other analytical methods to verify identity, purity, and stereochemical composition. We provide a comprehensive Certificate of Analysis (COA) with every shipment, ensuring full traceability and compliance with global pharmaceutical standards.

The product is packaged in 25kg cardboard drums to ensure stability during transit, though custom packaging solutions are available according to customer specified requirements. Proper handling is essential to maintain product integrity. We recommend storing the material in a cool and dry well-closed container, keeping it away from moisture and strong light or heat sources. By adhering to these storage guidelines, customers can ensure the long-term stability and performance of the chemical in their inventory.