Intermediates

1,3-Difluoroacetone

  • CAS No.453-14-5
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 1,3-Difluoroacetone (CAS 453-14-5) serving as a critical fluorinated building block for pharmaceutical and agrochemical synthesis.

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Product Technical Details

Product Overview

1,3-Difluoroacetone represents a vital component in the realm of modern organofluorine chemistry. As a specialized fluorinated ketone, this compound serves as an essential building block for the construction of complex molecular architectures found in advanced pharmaceuticals and agrochemicals. The introduction of fluorine atoms into organic molecules often significantly enhances metabolic stability, bioavailability, and lipophilicity, making this intermediate highly sought after in medicinal chemistry research and development.

Our facility specializes in the production of high-quality fluorinated intermediates, ensuring that every batch of 1,3-Difluoroacetone meets rigorous international standards. We understand the critical nature of supply chain reliability for research institutions and manufacturing plants alike. Therefore, we have established a robust production platform that integrates raw material procurement, advanced fluorination technology, and stringent quality control measures to deliver consistent product performance.

Chemical Specifications

PropertySpecification
CAS Number453-14-5
Molecular FormulaC3H4F2O
Molecular Weight94.06 g/mol
Density1.092 g/cm3
Boiling Point85.7ºC at 760 mmHg
Flash Point22ºC
PurityHigh Purity Grade

Industrial Applications

The versatility of 1,3-Difluoroacetone allows it to be utilized across multiple high-value industries. Its unique chemical structure enables diverse synthetic transformations, making it a preferred choice for chemists designing new active ingredients.

  • Pharmaceutical Synthesis: Widely used in the development of kinase inhibitors and other therapeutic agents where fluorine substitution is critical for drug efficacy.
  • Agrochemical Development: Serves as a key precursor in the manufacture of novel pesticides and herbicides with improved environmental profiles.
  • New Materials: Employed in the synthesis of specialized polymers and functional materials requiring fluorinated backbones for enhanced performance.
  • Research and Development: An essential reagent for academic and industrial laboratories focusing on organofluorine chemistry and method development.

Quality Assurance and Supply Chain

Shanghai Fluorine Technology is committed to providing a complete fluorochemical products and technology platform. We offer convenient one-stop services that streamline the procurement process for our global clientele. Our quality assurance protocol includes comprehensive testing at every stage of production, from raw material intake to final product release. Each shipment is accompanied by a Certificate of Analysis (COA) to verify compliance with specified parameters.

Safety is paramount when handling fluorinated compounds. Given the flash point of 22ºC, proper storage and handling procedures must be followed to ensure workplace safety. We provide detailed safety data sheets and technical support to assist customers in integrating this material into their processes safely and efficiently. Our logistics network ensures timely delivery of bulk quantities while maintaining the integrity of the product during transit. Partner with us for reliable supply, competitive bulk pricing, and expert technical support in fluorine chemistry.