1,4-Bis(diphenylphosphino)butane
- CAS No.7688-25-7
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 1,4-Bis(diphenylphosphino)butane ligand for pharmaceutical synthesis. ≥98% purity, stable supply, and global shipping available.
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Product Overview
1,4-Bis(diphenylphosphino)butane, commonly abbreviated as DPPB, is a highly valued bidentate phosphine ligand utilized extensively in organometallic chemistry and pharmaceutical manufacturing. Our facility specializes in the production of this critical intermediate, ensuring consistent quality for complex synthetic routes. As a key component in homogeneous catalysis, this compound facilitates various coupling reactions essential for developing advanced therapeutic agents.
We understand the stringent requirements of the pharmaceutical industry. Therefore, our manufacturing process adheres to rigorous quality control standards to deliver material with exceptional purity and stability. This product serves as a foundational building block for chemists aiming to achieve high yields and selectivity in their synthesis protocols.
Chemical Properties And Specifications
The chemical integrity of 1,4-Bis(diphenylphosphino)butane is maintained through careful synthesis and purification. The butane backbone provides optimal flexibility for coordinating with transition metals, while the diphenylphosphino groups offer robust stability under reaction conditions. Below are the detailed technical specifications for our standard grade material:
| Parameter | Value |
|---|---|
| CAS Number | 7688-25-7 |
| Molecular Formula | C28H28P2 |
| Molecular Weight | 426.47 g/mol |
| Appearance | White crystals powder |
| Purity | ≥98% |
| Melting Point | 132-136 °C |
| Boiling Point | 542 °C at 760 mmHg |
| Loss On Drying | ≤0.2% |
Industrial Applications
This phosphine ligand is primarily employed as a pharmaceutical intermediate. It plays a pivotal role in palladium-catalyzed cross-coupling reactions, such as Suzuki-Miyaura and Heck reactions, which are fundamental in constructing carbon-carbon bonds for active pharmaceutical ingredients (APIs). Additionally, it is used in the synthesis of fine chemicals and specialized organic compounds where precise stereocontrol is required.
- Facilitates efficient catalytic cycles in homogeneous catalysis.
- Enhances reaction selectivity and yield in complex molecule synthesis.
- Compatible with a wide range of transition metal complexes.
- Ideal for scaling up from laboratory research to industrial production.
Quality Assurance And Packaging
Quality is our paramount commitment. Every batch of 1,4-Bis(diphenylphosphino)butane undergoes comprehensive testing using advanced analytical techniques including HPLC and NMR to verify identity and purity. We provide a Certificate of Analysis (COA) with every shipment to ensure transparency and compliance with your internal quality standards.
Our standard packaging consists of 25 kg drums, designed to protect the material from moisture and oxidation during transit. However, we offer flexible packaging solutions tailored to specific customer requirements. Proper storage is essential to maintain product integrity. We recommend keeping the container tightly closed in a cool, dry place, away from direct sunlight and incompatible substances.
Why Choose Our Supply
As a global manufacturer with decades of experience in chemical intermediates, we offer competitive bulk pricing without compromising on quality. Our supply chain is robust, ensuring timely delivery to support your production schedules. Whether you require material for research and development or large-scale manufacturing, our team is ready to provide technical support and reliable supply solutions.
