Intermediates

1,4-Difluoro-2-methyl-5-nitrobenzene

  • CAS No.141412-60-4
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 1,4-Difluoro-2-methyl-5-nitrobenzene (CAS 141412-60-4) designed for advanced organic synthesis and pharmaceutical intermediate applications.

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Product Technical Details

Product Overview

1,4-Difluoro-2-methyl-5-nitrobenzene is a specialized fluorinated aromatic compound widely recognized for its utility in complex organic synthesis. As a key building block, this chemical features a unique substitution pattern that facilitates nucleophilic aromatic substitution reactions. Our manufacturing process ensures consistent quality and high purity levels, making it an ideal choice for research and industrial scale production.

The presence of both fluoro and nitro groups on the benzene ring activates the molecule for various transformation pathways. This versatility allows chemists to develop novel pharmaceutical agents and agrochemical formulations with enhanced biological activity. We adhere to strict quality control protocols to guarantee that every batch meets international standards for chemical intermediates.

Technical Specifications

ParameterValue
CAS Number141412-60-4
Molecular FormulaC7H5F2NO2
Molecular Weight173.12 g/mol
AppearanceColorless to light yellow powder
Purity≥98%
Water Content≤0.5%
Density1.374 g/cm3
Boiling Point251°C
Flash Point121°C
Refractive Index1.508

Industrial Applications

This compound serves as a critical intermediate in the synthesis of advanced pharmaceuticals and agrochemicals. The fluorine atoms provide metabolic stability to final drug candidates, while the nitro group offers a handle for further reduction or functionalization. Common uses include the production of kinase inhibitors, receptor modulators, and specialized crop protection agents.

  • Pharmaceutical intermediate for targeted therapy development
  • Agrochemical precursor for herbicide and pesticide synthesis
  • Research chemical for organic methodology studies
  • Building block for fluorinated polymer modifications

Quality Assurance and Handling

We prioritize safety and quality in every shipment. Each drum is accompanied by a Certificate of Analysis (COA) verifying purity and physical constants. The product is packaged in secure plastic or plastic-coated iron drums to prevent moisture absorption and contamination during transit.

Proper storage is essential to maintain product integrity. Store in a cool, dry, and well-ventilated area away from incompatible materials. Keep containers tightly closed when not in use. Our logistics team ensures compliant shipping under UN2242 regulations, guaranteeing safe delivery to your facility globally.