Intermediates

1-(2-Chloro-4-hydroxyphenyl)-3-cyclopropylurea

  • CAS No.796848-79-8
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity pharmaceutical intermediate used in the synthesis of Lenvatinib. Available in bulk quantities with full COA support and reliable global shipping.

Request Bulk Pricing

Product Technical Details

Product Overview

1-(2-Chloro-4-hydroxyphenyl)-3-cyclopropylurea is a specialized organic compound primarily utilized as a critical building block in the pharmaceutical industry. This urea derivative serves as a key intermediate in the multi-step synthesis of advanced kinase inhibitors. Our manufacturing facility ensures that every batch meets rigorous quality standards suitable for large-scale API production. The compound is characterized by its stable chemical structure and high reactivity profile, making it an essential component for medicinal chemistry research and development.

We understand the importance of consistency in pharmaceutical supply chains. Therefore, our production processes are designed to maintain strict control over impurities and stereochemistry. This chemical is not intended for direct human consumption but rather for professional use in licensed laboratories and manufacturing plants focused on drug substance creation.

Technical Specifications

Our quality control team employs advanced analytical techniques including HPLC, NMR, and Mass Spectrometry to verify the identity and purity of each lot. The physical properties are consistent with theoretical values, ensuring reliable performance in downstream synthesis reactions. Below are the detailed specifications for our standard commercial grade material.

ParameterSpecification
Chemical Name1-(2-Chloro-4-hydroxyphenyl)-3-cyclopropylurea
CAS Number796848-79-8
Molecular FormulaC10H11ClN2O2
Molecular Weight226.66 g/mol
AppearanceWhite or off-white powder
Purity≥99.0%
Loss On Drying≤0.2%
Moisture Content≤0.01%
Density1.4±0.1 g/cm3
Boiling Point364.6±42.0 °C at 760 mmHg

Quality Assurance and Safety

Safety and compliance are paramount in our operations. All products are handled according to international chemical safety regulations. We provide comprehensive documentation including Certificates of Analysis (COA), Material Safety Data Sheets (MSDS), and method validation reports upon request. Our packaging ensures protection against moisture and light degradation during transit.

  • Strict quality control protocols at every production stage
  • Batch traceability for full supply chain transparency
  • Compliance with international shipping regulations for chemicals
  • Stable supply chain capable of meeting bulk demand

Industrial Applications

This intermediate is predominantly used in the synthesis of targeted therapy agents. It acts as a precursor in the construction of complex molecular architectures required for modern oncology treatments. Researchers and process chemists value this material for its reliability in coupling reactions and its compatibility with various synthetic routes. We support both R&D scale requirements and commercial manufacturing volumes.

For storage, keep the container tightly closed in a cool, dry, and well-ventilated area. Protect from strong light and heat sources to maintain stability. Always follow standard laboratory safety procedures when handling this substance. Our technical support team is available to assist with application-specific inquiries and custom synthesis requirements.