1-(2-Methoxyphenyl)piperazine hydrochloride
- CAS No.5464-78-8
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity pharmaceutical intermediate used primarily in the synthesis of naftopidil and other therapeutic agents. Available in bulk quantities with strict quality control.
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Product Overview
1-(2-Methoxyphenyl)piperazine hydrochloride is a specialized organic compound serving as a critical building block in the pharmaceutical industry. This chemical intermediate is characterized by its high stability and reactivity, making it an essential precursor for the synthesis of various therapeutic agents. Our manufacturing process ensures that every batch meets rigorous international standards for purity and consistency. As a leading supplier, we understand the importance of reliable supply chains in drug development and production.
The compound is supplied as a crystalline powder, typically off-white or white in appearance. Its physical properties, including a defined melting point and specific density, are tightly controlled to facilitate smooth downstream processing. We prioritize quality assurance at every stage, from raw material sourcing to final packaging, ensuring that our clients receive materials that support efficient synthesis routes.
Technical Specifications
Quality parameters are verified through advanced analytical methods including HPLC and NMR spectroscopy. The following table outlines the key physical and chemical properties associated with this product grade.
| Parameter | Specification |
|---|---|
| CAS Number | 5464-78-8 |
| Molecular Formula | C11H17ClN2O |
| Molecular Weight | 228.719 |
| Appearance | Off-white or white powder |
| Assay (Purity) | ≥99.0% |
| Water Content | ≤0.50% |
| Melting Point | 217-219 °C |
| Storage Condition | -20°C Freezer |
These specifications are guaranteed via a Certificate of Analysis (COA) provided with each shipment. Maintaining low water content and high assay values is crucial for preventing side reactions during subsequent synthetic steps.
Industrial Applications
This intermediate is predominantly utilized in the manufacture of pharmaceutical products. Its primary application lies in the synthesis of naftopidil, an agent used in the management of benign prostatic hyperplasia. The structural integrity of the piperazine ring and the methoxy substitution pattern are vital for the biological activity of the final drug substance.
- Essential precursor for alpha-adrenergic antagonist synthesis.
- Used in developing novel neurological therapeutics.
- Compatible with various organic synthesis routes.
- Supports large-scale industrial manufacturing processes.
Beyond its primary use, this compound serves as a valuable building block for research and development in medicinal chemistry. Our team provides technical support to help optimize synthesis routes for specific client requirements.
Storage and Handling
Proper storage is essential to maintain the stability and quality of 1-(2-Methoxyphenyl)piperazine hydrochloride. The product should be stored in a cool, dry place, ideally in a freezer at -20°C. Containers must be kept tightly closed to prevent moisture absorption and contamination. When handling, standard laboratory safety protocols should be followed, including the use of appropriate personal protective equipment.
We offer flexible packaging options, typically 25kg per drum, but can customize according to customer requirements. Global logistics capabilities ensure timely delivery while maintaining cold chain integrity where necessary. Contact our sales team for bulk pricing and detailed regulatory documentation.
