1-(4-Aminophenyl)-4-(4-Hydroxyphenyl)piperazine
- CAS No.74853-08-0
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity pharmaceutical intermediate used primarily in the synthesis of antifungal agents like Posaconazole. Available in bulk quantities with strict quality control and global shipping options.
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Product Overview
1-(4-Aminophenyl)-4-(4-Hydroxyphenyl)piperazine is a sophisticated organic compound recognized for its critical role in modern pharmaceutical synthesis. As a key building block, this substance serves as an essential intermediate in the production of advanced antifungal medications. Our facility specializes in the manufacturing of this high-value chemical, ensuring that every batch meets rigorous international standards for purity and consistency. The molecular structure features a piperazine core substituted with aminophenyl and hydroxyphenyl groups, providing unique reactivity profiles suitable for complex organic transformations.
We understand the demands of the pharmaceutical industry, where precision and reliability are paramount. Therefore, our production processes are designed to minimize impurities and maximize yield. This product is specifically engineered to support the synthesis of triazole antifungal agents, contributing to the global supply chain of vital therapeutic solutions. Whether for research and development or large-scale commercial production, our material provides a dependable foundation for your chemical processes.
Technical Specifications
Quality control is integral to our operations. Each lot undergoes comprehensive analytical testing to verify compliance with specified parameters. The following table outlines the standard physical and chemical properties associated with this grade:
| Parameter | Specification |
|---|---|
| CAS Number | 74853-08-0 |
| Molecular Formula | C16H19N3O |
| Molecular Weight | 269.342 g/mol |
| Appearance | Off-white to light brown powder |
| Assay (Purity) | ≥99.0% |
| Loss on Drying | ≤0.5% |
| Density | 1.2±0.1 g/cm3 |
| Boiling Point | 532.8±50.0 °C at 760 mmHg |
| Flash Point | 276.0±30.1 °C |
Industrial Applications
The primary application of 1-(4-Aminophenyl)-4-(4-Hydroxyphenyl)piperazine lies within the pharmaceutical sector, specifically as an intermediate for Posaconazole synthesis. Posaconazole is a broad-spectrum antifungal agent used to treat invasive fungal infections. The integrity of the final drug product depends heavily on the quality of its precursors. Our intermediate ensures optimal reaction kinetics and minimizes downstream purification challenges. Beyond antifungal agents, this compound may also serve as a versatile building block in the development of other neurological therapeutics or complex organic molecules requiring piperazine scaffolds.
Quality Assurance and Manufacturing
Our manufacturing facility adheres to strict quality management systems. We employ advanced analytical techniques, including HPLC and NMR, to validate the chemical identity and purity of each batch. Documentation such as Certificates of Analysis (COA) is provided with every shipment to ensure full traceability. Our team of chemists continuously monitors production variables to maintain industrial purity levels that exceed market expectations. This commitment to quality reduces risk for our partners and ensures smooth integration into your synthesis routes.
Packaging and Storage
To preserve stability and prevent degradation, proper handling is essential. The standard packaging configuration is 25 kg per drum, though we offer flexible packaging solutions tailored to specific customer requirements. Storage should be maintained in a cool, ventilated area away from direct sunlight and moisture. Containers must remain tightly sealed when not in use to prevent contamination. We support global logistics networks to ensure timely delivery while maintaining product integrity throughout the supply chain. For detailed safety data or custom formulation inquiries, our technical support team is available to assist with your specific project needs.
