Intermediates

1,1,1-Trifluoroacetone

  • CAS No.421-50-1
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 1,1,1-Trifluoroacetone (CAS 421-50-1) supplied for advanced organic synthesis. Ideal trifluoromethylation reagent with strict quality control.

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Product Technical Details

Product Overview

1,1,1-Trifluoroacetone is a specialized fluorinated ketone serving as a critical intermediate in modern organic chemistry. As a versatile building block, it facilitates the introduction of trifluoromethyl groups into complex molecular structures. Our facility produces this compound under stringent quality management systems to ensure consistency for pharmaceutical and agrochemical research applications.

This chemical is characterized by its high reactivity and stability under controlled conditions. It is widely recognized in the industry for its utility in synthesizing heterocyclic compounds and specialized polymers. The presence of the trifluoromethyl group enhances the metabolic stability and lipophilicity of downstream products, making it a valuable asset in medicinal chemistry design.

Technical Specifications

We adhere to rigorous analytical standards to guarantee product performance. Each batch undergoes comprehensive testing using gas chromatography and Karl Fischer titration. The following table outlines the key physical properties and quality parameters associated with our standard grade material.

ParameterSpecificationTypical Result
AppearanceColorless liquidColorless liquid
CAS Number421-50-1421-50-1
Molecular FormulaC3H3F3OC3H3F3O
Molecular Weight112.05 g/mol112.05 g/mol
Purity (Assay)≥99.0%99.34%
Moisture Content≤0.2%0.0125%
Density1.252 g/mL at 25 °CConforms
Boiling Point22 °CConforms

Industrial Applications

The primary use of 1,1,1-Trifluoroacetone lies in its function as a trifluoromethylation reagent. It is extensively utilized in the preparation of fine chemicals and advanced intermediates. Key application areas include:

  • Synthesis of fluorinated pharmaceuticals where metabolic stability is required.
  • Development of agrochemical active ingredients with enhanced environmental profiles.
  • Construction of specialized polymer matrices requiring fluorine modification.
  • Research and development in organofluorine chemistry laboratories.

Quality Assurance And Safety

Our manufacturing process prioritizes safety and environmental compliance. We provide a Certificate of Analysis (COA) with every shipment to verify conformity with stated specifications. Proper handling is essential due to the volatile nature of low molecular weight ketones. Personnel should utilize appropriate personal protective equipment including chemical-resistant gloves and eye protection.

Storage conditions are critical for maintaining product integrity. The material should be kept in a cool, well-ventilated area away from incompatible substances. We recommend storage temperatures between 2-8°C to minimize degradation over time. Our logistics team ensures secure packaging to prevent leakage during global transit.

Why Choose Our Supply

As a dedicated manufacturer, we offer competitive bulk pricing without compromising on purity. Our supply chain is optimized for reliability, ensuring timely delivery for your production schedules. We support long-term partnerships with transparent communication and technical documentation. Contact our sales team for custom packaging options and detailed safety data sheets.