1,1-Difluoroacetone
- CAS No.431-05-0
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 1,1-Difluoroacetone (CAS 431-05-0) designed for pharmaceutical and agrochemical synthesis. Reliable bulk supply with full technical support.
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Product Overview
1,1-Difluoroacetone represents a critical fluorinated building block within the realm of advanced organic synthesis. As a specialized ketone derivative featuring geminal difluoro substitution, this compound offers unique reactivity profiles that are highly valued in the development of novel pharmaceutical agents and agrochemical formulations. The introduction of fluorine atoms into organic molecules often enhances metabolic stability and bioavailability, making this intermediate a strategic choice for medicinal chemists aiming to optimize lead compounds.
Our manufacturing process ensures consistent quality and high purity levels, adhering to strict industrial standards. We understand the sensitivities involved in handling fluorinated reagents, and our production facilities are equipped to manage volatile organic compounds safely. This product serves as a versatile precursor for various chemical transformations, enabling researchers to introduce fluorine motifs efficiently into complex molecular architectures.
Key Specifications
| Property | Specification |
|---|---|
| Product Name | 1,1-Difluoroacetone |
| CAS Number | 431-05-0 |
| Molecular Formula | C3H4F2O |
| Molecular Weight | 94.06 g/mol |
| Purity | >98.0% (GC) |
| Density | 1.088 g/cm3 |
| Boiling Point | 45.3°C at 760 mmHg |
| Flash Point | 1.6°C |
| Refractive Index | 1.328 |
| Vapor Pressure | 350 mmHg at 25°C |
Industrial Applications
The primary utility of 1,1-Difluoroacetone lies in its role as a synthetic intermediate for high-value end products. In the pharmaceutical sector, it is utilized in the synthesis of kinase inhibitors and other therapeutic candidates where fluorine substitution is required to modulate pharmacokinetic properties. The compound's reactivity allows for diverse functionalization, supporting the creation of complex heterocyclic systems often found in modern drug molecules.
Beyond pharmaceuticals, this fluorinated ketone is instrumental in agrochemical research. It aids in the development of new pesticides and herbicides that require enhanced environmental stability and potency. Additionally, materials science researchers leverage this compound to create specialized polymers and fluorinated materials with unique thermal and chemical resistance properties. Our commitment to providing a complete fluorochemical platform ensures that clients receive not just a product, but a comprehensive solution for their synthesis needs.
Quality Assurance and Supply Chain
We prioritize quality control at every stage of production. Each batch of 1,1-Difluoroacetone undergoes rigorous testing using advanced analytical techniques such as Gas Chromatography (GC) and Nuclear Magnetic Resonance (NMR) to verify identity and purity. A Certificate of Analysis (COA) is provided with every shipment to guarantee compliance with specified parameters.
- Consistent batch-to-batch reproducibility for reliable research outcomes.
- Secure packaging designed to maintain stability during international transport.
- Scalable production capacity to meet both R&D and commercial manufacturing demands.
- Dedicated technical support team available for synthesis route optimization.
Choosing our company means partnering with a global manufacturer dedicated to safety, compliance, and excellence. We manage the entire industrial chain from raw material procurement to final quality control, ensuring a seamless supply experience for our international clientele.
