1,2,3,4-Tetrahydro-benzo[b]azepin-5-one
- CAS No.1127-74-8
- GradeIndustrial / Pharmaceutical
- Availabilityβ In Stock
High-purity pharmaceutical intermediate used in the synthesis of Conivaptan hydrochloride. Available in bulk quantities with strict quality control and global shipping.
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Product Overview
1,2,3,4-Tetrahydro-benzo[b]azepin-5-one is a specialized heterocyclic compound serving as a critical building block in modern pharmaceutical synthesis. Identified by CAS number 1127-74-8, this chemical intermediate is characterized by its robust molecular structure and high reactivity, making it indispensable for the production of advanced therapeutic agents. Our manufacturing process ensures that each batch meets stringent purity standards, suitable for complex organic synthesis pathways required in the development of cardiovascular and renal treatments.
As a leading supplier in the fine chemicals industry, we understand the importance of consistency and reliability. This compound is engineered to facilitate efficient reaction rates while minimizing impurities that could affect downstream processing. The molecular formula C10H11NO represents a versatile scaffold used by medicinal chemists to construct larger, biologically active molecules. Our commitment to quality begins at the raw material sourcing stage and continues through rigorous final testing.
Technical Specifications
To guarantee performance in your synthesis protocols, we provide comprehensive physical and chemical data for every shipment. The following table outlines the key parameters verified by our quality control laboratory. We maintain tight controls over melting point and assay values to ensure reproducibility in your manufacturing operations.
| Parameter | Value |
|---|---|
| Appearance | Yellow to dark green powder |
| Assay | ≥98.0% |
| Molecular Formula | C10H11NO |
| Molecular Weight | 161.200 |
| Melting Point | 87-88°C |
| Boiling Point | 314.6±12.0 °C at 760 mmHg |
| Density | 1.1±0.1 g/cm3 |
Industrial Applications
The primary application of 1,2,3,4-Tetrahydro-benzo[b]azepin-5-one lies in the pharmaceutical sector, specifically as a key intermediate in the synthesis of Conivaptan hydrochloride. This downstream product is utilized in the management of specific medical conditions related to fluid balance. Beyond this specific pathway, the chemical structure offers potential utility in the development of other nitrogen-containing heterocycles used in medicinal chemistry research.
Our clients value this intermediate for its stability under standard storage conditions and its compatibility with various synthetic routes. Whether used in pilot-scale experiments or full-scale commercial production, the material delivers consistent performance. We support R and D teams with technical data packages that streamline regulatory filings and process validation. The ketone functionality within the azepine ring allows for diverse chemical modifications, enabling chemists to explore structure-activity relationships effectively.
Quality Assurance and Storage
Quality is the cornerstone of our operation. Each production lot undergoes multiple analytical checks, including HPLC and NMR spectroscopy, to confirm identity and purity. We provide a Certificate of Analysis (COA) with every order, ensuring full transparency and traceability. Proper storage is essential to maintain the integrity of the product over time.
- Store in a cool, ventilated place away from direct sunlight.
- Keep containers tightly closed when not in use to prevent moisture absorption.
- Handle with appropriate personal protective equipment during weighing and transfer.
Our facility adheres to strict environmental and safety regulations, ensuring that the production process minimizes ecological impact. We are committed to sustainable chemistry practices while maintaining cost-effectiveness for our partners. Regular audits and process optimizations allow us to offer competitive bulk pricing without compromising on quality standards. We offer flexible packaging options, including 25 kg drums, customized to meet your logistical requirements. Our global supply chain ensures timely delivery to research facilities and manufacturing plants worldwide. Partner with us for reliable access to high-quality pharmaceutical intermediates that drive innovation in drug development.
