1,2,3-Trifluorobenzene
- CAS No.1489-53-8
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High purity 1,2,3-Trifluorobenzene (CAS 1489-53-8) designed for advanced pharmaceutical synthesis and organic chemistry applications. Available in bulk with comprehensive quality documentation.
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Product Overview
1,2,3-Trifluorobenzene is a specialized fluorinated aromatic compound widely recognized for its critical role in modern medicinal chemistry and organic synthesis. As a key building block, this vicinal trifluorinated benzene derivative offers unique reactivity profiles that enable the construction of complex molecular architectures. Our manufacturing process ensures exceptional consistency, making it an ideal choice for research and development teams focused on novel drug discovery and advanced material science.
We understand the stringent requirements of the pharmaceutical industry. Therefore, every batch of 1,2,3-Trifluorobenzene undergoes rigorous quality control protocols to guarantee high purity and low moisture content. This commitment to excellence supports our clients in achieving reliable reaction outcomes and minimizing downstream purification challenges.
Technical Specifications
Our production facility adheres to strict international standards to deliver products that meet or exceed industry expectations. The following table outlines the typical physical and chemical properties associated with this grade. Custom specifications may be available upon request for specific project requirements.
| Parameter | Specification | Typical Result |
|---|---|---|
| Appearance | Colorless to light yellow liquid | Conforms |
| CAS Number | 1489-53-8 | 1489-53-8 |
| Molecular Formula | C6H3F3 | C6H3F3 |
| Molecular Weight | 132.08 g/mol | 132.08 |
| Assay (GC) | ≥99.0% | 99.2% |
| Water Content | ≤0.2% | 0.12% |
| Boiling Point | 94-95°C | 94.5°C |
| Density | 1.28 g/cm3 | 1.28 |
Industrial Applications
The primary utility of 1,2,3-Trifluorobenzene lies in its function as a versatile intermediate for the synthesis of active pharmaceutical ingredients (APIs). The presence of three fluorine atoms in a vicinal arrangement significantly influences the electronic and steric properties of the resulting molecules, often enhancing metabolic stability and bioavailability in drug candidates.
Key application areas include:
- Pharmaceutical Intermediate Synthesis: Used extensively in the production of various therapeutic agents requiring fluorinated aromatic cores.
- Agrochemical Development: Serves as a precursor for high-performance pesticides and herbicides.
- Material Science: Utilized in the creation of specialized polymers and liquid crystals.
- Organic Research: A valuable reagent for exploring new fluorination methodologies and reaction mechanisms.
Storage and Handling
To maintain product integrity, 1,2,3-Trifluorobenzene should be stored in a cool, well-ventilated area away from direct sunlight and heat sources. Containers must remain tightly sealed when not in use to prevent moisture absorption and contamination. We recommend following standard safety procedures for handling fluorinated organic compounds, including the use of appropriate personal protective equipment (PPE) such as gloves and safety goggles.
Packing options typically include 200 kg drums, though we offer flexible packaging solutions tailored to customer logistics and volume requirements. Each shipment is accompanied by a Certificate of Analysis (COA) to verify quality parameters. For bulk pricing inquiries or technical support regarding synthesis routes, please contact our global sales team.
