1,2,4,5-Tetrafluorobenzene
- CAS No.327-54-8
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity fluorinated aromatic intermediate designed for pharmaceutical and agrochemical synthesis with consistent quality.
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Product Overview
1,2,4,5-Tetrafluorobenzene represents a cornerstone compound in the realm of organofluorine chemistry. As a symmetrical tetra-substituted aromatic system, it provides unique electronic properties that are highly sought after in complex molecular construction. This transparent colorless liquid is engineered for professionals who require reliability and precision in their synthetic workflows. Our production processes adhere to strict international standards, ensuring that every drum delivered meets the exacting requirements of R&D laboratories and large-scale manufacturing facilities.
The strategic placement of fluorine atoms on the benzene ring significantly alters the chemical reactivity compared to non-fluorinated analogs. This makes 1,2,4,5-Tetrafluorobenzene an ideal candidate for nucleophilic aromatic substitution, allowing chemists to introduce diverse functional groups with high regioselectivity. Whether you are developing novel therapeutic candidates or engineering advanced polymers, this intermediate provides the foundational structure necessary for innovation.
Technical Specifications
| Parameter | Value |
|---|---|
| CAS Number | 327-54-8 |
| Molecular Formula | C6H2F4 |
| Molecular Weight | 150.07 g/mol |
| Appearance | Transparent Colorless Liquid |
| Density | 1.344 g/mL at 25 °C |
| Boiling Point | 90 °C |
| Melting Point | 4 °C |
| Flash Point | 61 °F |
| Refractive Index | n20/D 1.407 |
| Purity | High Performance Grade |
Industrial Applications
The versatility of this fluorinated building block extends across several critical industries. In pharmaceutical research and development, fluorine incorporation is a key strategy to improve the pharmacokinetic profile of drug candidates. 1,2,4,5-Tetrafluorobenzene serves as a vital precursor for creating active pharmaceutical ingredients (APIs) that require enhanced metabolic stability and lipid solubility. Furthermore, the agrochemical sector utilizes this compound to develop next-generation pesticides that offer greater efficacy and reduced environmental impact.
Beyond life sciences, the material science sector leverages this chemical for creating high-performance polymers and electronic materials. The strong carbon-fluorine bonds contribute to thermal stability and chemical resistance in final products. Our clients rely on this intermediate for:
- Synthesis of complex pharmaceutical intermediates
- Development of novel agrochemical formulations
- Production of fluorinated polymers and resins
- Research into organic electronic materials
- Custom synthesis projects requiring fluorinated aromatics
Quality Assurance and Storage
Quality consistency is the backbone of our supply chain. We implement a comprehensive quality control system that monitors every stage of production, from raw material procurement to final packaging. Each shipment is supported by detailed documentation, including a Certificate of Analysis (COA) and safety data sheets. This transparency ensures that your production schedules remain uninterrupted and compliant with regulatory standards.
Regarding storage and handling, 1,2,4,5-Tetrafluorobenzene should be kept in a cool, well-ventilated flammables area. Containers must be tightly closed when not in use to prevent contamination or evaporation. While stable under normal temperatures and pressures, standard safety protocols for handling flammable liquids should always be observed. Our team is available to provide technical guidance on safe handling practices and integration into your specific manufacturing processes. Choose us for a partnership built on quality, reliability, and technical expertise in fluorine chemistry.
