Intermediates

1,2-Bis(dimethylphosphino)ethane

  • CAS No.23936-60-9
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity 1,2-Bis(dimethylphosphino)ethane (CAS 23936-60-9) for catalysis and pharmaceutical synthesis. ≥98% purity with global shipping and COA.

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Product Technical Details

Product Overview

1,2-Bis(dimethylphosphino)ethane, frequently abbreviated as dmpe, is a premier bidentate phosphine ligand utilized extensively in organometallic chemistry and advanced pharmaceutical synthesis. This colorless liquid represents a critical building block for creating stable metal complexes used in homogeneous catalysis. Our manufacturing process ensures exceptional purity levels, making it an ideal choice for researchers and industrial chemists requiring reliable reagents for sensitive reactions. The compound features two dimethylphosphino groups linked by an ethylene bridge, providing unique steric and electronic properties that enhance catalytic performance. Its stability and reactivity profile make it a preferred choice over monodentate ligands for processes requiring robust coordination geometry.

Technical Specifications

We adhere to strict quality control protocols to guarantee consistency across every batch. The following table outlines the key physical and chemical properties of our premium grade product. Each shipment is accompanied by a Certificate of Analysis to verify compliance with stated parameters.

ParameterSpecification
CAS Number23936-60-9
AppearanceColorless Liquid
Purity≥98%
Molecular FormulaC6H16P2
Molecular Weight150.14 g/mol
Density0.9 g/mL at 25 °C
Boiling Point180 °C
Flash Point-16 °C

Industrial Applications

This versatile phosphine ligand serves as a fundamental component in the development of catalysts for hydrogenation, hydroformylation, and coupling reactions. In the pharmaceutical sector, it acts as a crucial intermediate for synthesizing complex active pharmaceutical ingredients where precise stereocontrol is required. Its ability to form chelate complexes with transition metals such as palladium, platinum, and nickel makes it indispensable for modern organic synthesis workflows. Additionally, it is employed in material science research for creating specialized polymeric structures and nanomaterials. Researchers value this intermediate for its ability to facilitate cross-coupling reactions which are pivotal in constructing complex molecular architectures found in modern therapeutics.

Storage and Safety Handling

Due to its flammable nature and sensitivity to oxidation, proper handling procedures are essential. The product should be stored in a cool, dry, and well-ventilated area designated for flammable materials. Containers must remain tightly closed when not in use to prevent degradation from atmospheric moisture or oxygen. We recommend handling this chemical under an inert atmosphere, such as nitrogen or argon, to maintain optimal purity levels during laboratory or production scale operations. Personal protective equipment including gloves and safety goggles should be worn at all times.

Quality Assurance and Supply

As a global manufacturer, we are committed to delivering high-performance chemicals that meet international standards. Our production facilities utilize advanced distillation and purification techniques to achieve the specified purity of ≥98%. We offer flexible packaging options, including standard 25 kg drums or customized solutions based on specific client requirements. Our logistics network ensures timely global delivery with full documentation support. For technical inquiries or bulk pricing requests, our expert team is available to provide comprehensive assistance.