Intermediates

1,2-Dichloro-4-fluorobenzene

  • CAS No.1435-49-0
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity 1,2-Dichloro-4-fluorobenzene (CAS 1435-49-0) supplied for pharmaceutical synthesis. Reliable quality, bulk availability, and strict quality control for industrial applications.

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Product Technical Details

Product Overview

1,2-Dichloro-4-fluorobenzene is a critical fluorinated aromatic compound widely recognized for its versatility in organic synthesis and industrial chemical manufacturing. As a key building block, this substance serves as an essential precursor in the development of complex pharmaceutical intermediates and advanced agrochemical formulations. Our facility specializes in the production of high-grade fluorinated benzenes, ensuring that every batch meets rigorous international standards for purity and consistency.

The unique structural configuration of this dichlorofluorobenzene isomer provides distinct reactivity profiles, making it highly valuable for nucleophilic aromatic substitution reactions. Manufacturers across the globe rely on this chemical for its stability and predictable performance during multi-step synthesis processes. We maintain a robust supply chain to support large-scale production needs while adhering to strict environmental and safety protocols.

Technical Specifications

Quality assurance is paramount in the supply of fine chemicals. Our 1,2-Dichloro-4-fluorobenzene undergoes comprehensive analytical testing to verify compliance with specified parameters. The following table outlines the standard physical and chemical properties associated with our premium grade product.

Parameter Specification
CAS Number 1435-49-0
Molecular Formula C6H3Cl2F
Molecular Weight 164.99 g/mol
Purity ≥98.0%
Appearance Transparent colorless to slightly yellow liquid
Density 1.403 g/mL at 25 °C
Boiling Point 172 °C
Melting Point -1 °C
Refractive Index 1.524

Industrial Applications

The primary application of 1,2-Dichloro-4-fluorobenzene lies within the pharmaceutical sector, where it functions as a vital intermediate for synthesizing active pharmaceutical ingredients (APIs). Its chemical structure allows for selective functionalization, enabling chemists to introduce specific substituents required for drug efficacy. Beyond pharmaceuticals, this compound is utilized in the production of specialized polymers and liquid crystals.

  • Pharmaceutical Intermediate Synthesis
  • Agrochemical Product Development
  • Organic Fluorine Chemical Manufacturing
  • Advanced Material Science Research

Storage and Handling

Proper storage conditions are essential to maintain the integrity of this chemical product. The substance should be kept in a tightly closed container within a cool, dry, and well-ventilated area. It is crucial to store the material away from incompatible substances, heat sources, sparks, and open flames to prevent potential hazards. Our packaging options include standard 25kg drums, designed to ensure safety during transportation and long-term storage. We recommend consulting the Safety Data Sheet (SDS) for detailed handling instructions and regulatory compliance information.