Intermediates

1-(2-Furoyl)piperazine

  • CAS No.40172-95-0
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 1-(2-Furoyl)piperazine (CAS 40172-95-0) designed for pharmaceutical synthesis, specifically as a key intermediate for Prazosin hydrochloride production.

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Product Technical Details

Product Overview

1-(2-Furoyl)piperazine represents a critical heterocyclic building block within modern medicinal chemistry and organic synthesis workflows. Characterized by its unique structural combination of a furan ring and a piperazine moiety linked via a carbonyl group, this compound serves as a versatile precursor for various therapeutic agents. Our facility produces this chemical under strict quality control protocols to ensure consistency for large-scale pharmaceutical manufacturing. The compound is highly valued for its reactivity and stability, making it an essential component in the development of complex pharmaceutical APIs.

As a dedicated manufacturer with decades of experience, we understand the importance of supply chain reliability for research and production teams. Our 1-(2-Furoyl)piperazine is synthesized using advanced organic chemistry techniques to minimize impurities and maximize yield. This commitment to excellence ensures that downstream processes, such as amide coupling or nucleophilic substitution, proceed with high efficiency. Whether used in laboratory-scale research or industrial production, our material provides a reliable foundation for chemical innovation.

Technical Specifications

To support rigorous quality assurance requirements, we provide comprehensive physical and chemical data for every batch. The following table outlines the key specifications that define the quality of our 1-(2-Furoyl)piperazine. Maintaining high purity is essential to prevent side reactions during subsequent synthesis steps.

ParameterSpecification
CAS Number40172-95-0
Molecular FormulaC9H12N2O2
Molecular Weight180.20 g/mol
AppearanceWhite to light yellow solid
Purity≥99.0%
Melting Point67-70 °C
Boiling Point137-140 °C (0.1 mmHg)
Density1.175 g/cm3
Refractive Index1.529

These physical properties, including the specific melting point range and density, serve as critical identity markers. Our quality control laboratory verifies each parameter against internal standards before release. The high purity level of 99 percent or greater ensures minimal interference in catalytic processes.

Industrial Applications

The primary application of 1-(2-Furoyl)piperazine lies in the pharmaceutical sector, specifically as an intermediate in the synthesis of antihypertensive medications. It is a known key precursor in the manufacturing process of Prazosin hydrochloride, a well-established alpha-1 adrenergic receptor antagonist. Beyond this specific use case, the chemical structure offers significant versatility for medicinal chemists exploring new heterocyclic compounds.

The piperazine ring provides a stable scaffold for further functionalization, while the furoyl group offers specific electronic properties useful in drug design. Researchers utilize this building block to develop novel therapeutic candidates targeting cardiovascular and neurological pathways. Our product supports both generic drug manufacturing and innovative new drug discovery programs. By providing a consistent supply of high-quality intermediates, we enable our partners to accelerate their development timelines.

Quality Assurance and Safety

Safety and quality are paramount in the handling of chemical intermediates. Our production facilities adhere to international safety standards and environmental regulations. Each shipment is accompanied by a Certificate of Analysis (COA) that details the test results for purity, identity, and physical constants. We recommend storing this product in a cool and dry environment, kept in a well-closed container to protect against moisture and strong light.

Proper storage conditions are essential to maintain the stability of the compound over time. Exposure to excessive heat or humidity should be avoided to prevent degradation. Our packaging solutions are designed to ensure integrity during global transit. We offer technical support to assist with handling guidelines and safety data sheet (SDS) information. Our team is committed to providing not just a product, but a comprehensive service that supports your operational safety and regulatory compliance needs.

Packaging and Logistics

We understand that efficient logistics are crucial for maintaining production schedules. 1-(2-Furoyl)piperazine is typically packed in 25kg cardboard drums, though custom packaging solutions are available according to customer specified requirements. Our logistics network ensures timely delivery to major pharmaceutical hubs worldwide. We work with trusted freight partners to handle hazardous materials compliance and customs documentation.

For bulk orders, we offer competitive pricing structures that reflect our commitment to long-term partnerships. Our manufacturing capacity allows us to scale production based on demand fluctuations. Contact our sales team today to discuss your specific volume requirements and receive a detailed quotation. We are ready to support your project with reliable supply and premium quality chemicals.