1-(2-Methyl-5-nitrophenyl)guanidine
- CAS No.152460-07-6
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High purity 1-(2-Methyl-5-nitrophenyl)guanidine (CAS 152460-07-6) designed for pharmaceutical synthesis. Reliable supply for Imatinib production with full quality documentation.
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Product Overview
1-(2-Methyl-5-nitrophenyl)guanidine is a critical organic compound widely recognized in the pharmaceutical industry for its role in the synthesis of advanced kinase inhibitors. Identified by CAS number 152460-07-6, this chemical intermediate serves as a foundational building block in the manufacturing process of Imatinib mesylate, a vital therapeutic agent used in oncology treatments. Our facility specializes in the production of this high-performance intermediate, ensuring that every batch meets stringent international quality standards required for pharmaceutical applications.
As a dedicated manufacturer, we understand the importance of consistency and purity in drug synthesis. This product is engineered to provide optimal reactivity and stability during downstream processing. The molecular structure, characterized by the formula C8H10N4O2, offers specific chemical properties that make it indispensable for constructing complex molecular frameworks found in modern targeted therapies. We commit to supplying global partners with material that supports efficient and safe production lines.
Technical Specifications
| Parameter | Specification |
|---|---|
| Chemical Name | 1-(2-Methyl-5-nitrophenyl)guanidine |
| CAS Number | 152460-07-6 |
| Molecular Formula | C8H10N4O2 |
| Molecular Weight | 194.19 g/mol |
| Appearance | Off-white solid |
| Purity | ≥99.0% |
| Density | 1.432 g/cm3 |
| Boiling Point | 426.748°C at 760 mmHg |
| Flash Point | 211.89°C |
| Refractive Index | 1.646 |
Industrial Applications
The primary application of 1-(2-Methyl-5-nitrophenyl)guanidine lies within the pharmaceutical sector, specifically as a key intermediate in the synthesis of Imatinib. Imatinib is a renowned tyrosine kinase inhibitor used to treat certain types of cancer, including chronic myeloid leukemia (CML) and gastrointestinal stromal tumors (GIST). The precision required in creating such medications demands raw materials of the highest caliber.
- Essential precursor for Imatinib mesylate synthesis.
- Utilized in the development of novel kinase inhibitors.
- Supports research and development in oncology therapeutics.
- Compatible with standard industrial organic synthesis routes.
Our product enables manufacturers to maintain high yields and minimize impurities in the final active pharmaceutical ingredient (API). By choosing our intermediate, production facilities can streamline their manufacturing process while adhering to regulatory compliance requirements.
Quality Assurance and Storage
Quality control is the cornerstone of our operation. Each production batch undergoes rigorous testing using advanced analytical methods such as HPLC and NMR to verify identity and purity. We provide a comprehensive Certificate of Analysis (COA) with every shipment, ensuring full traceability and transparency for our clients. Our manufacturing processes are designed to minimize environmental impact while maximizing product integrity.
Proper storage is essential to maintain the chemical stability of 1-(2-Methyl-5-nitrophenyl)guanidine. The product should be stored in a cool, dry, and well-closed container, protected from moisture and strong light or heat sources. We offer flexible packaging options, typically supplying in 25kg cardboard drums, but can accommodate custom requirements based on logistical needs. For bulk orders, our logistics team ensures safe and timely global delivery, supporting your supply chain continuity.
