1,3-Dichloro-1,1,3,3-tetraisopropyldisiloxane
- CAS No.69304-37-6
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High purity 1,3-Dichloro-1,1,3,3-tetraisopropyldisiloxane serves as a robust silylating agent for organic synthesis. Ideal for protecting groups in pharmaceutical and agrochemical intermediate production.
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Product Overview
1,3-Dichloro-1,1,3,3-tetraisopropyldisiloxane is a specialized organosilicon compound widely recognized for its effectiveness as a silylating agent in advanced organic synthesis. This reagent features a disiloxane backbone substituted with bulky isopropyl groups and reactive chloro functionalities. The steric hindrance provided by the isopropyl groups enhances stability during reaction processes, making it a preferred choice for introducing protecting groups onto hydroxyl functionalities.
Our manufacturing process ensures exceptional purity levels, suitable for demanding applications in the pharmaceutical and agrochemical sectors. As a key intermediate, this compound facilitates the construction of complex molecular architectures by protecting sensitive functional groups during multi-step synthesis routes.
Key Specifications
| Parameter | Specification |
|---|---|
| CAS Number | 69304-37-6 |
| Molecular Formula | C12H28Cl2OSi2 |
| Molecular Weight | 315.43 g/mol |
| Appearance | Colorless clear liquid |
| Purity (Assay) | 99.0% Min |
| Density | 0.986 g/mL at 25 °C |
| Boiling Point | 70 °C at 0.5 mm Hg |
| Refractive Index | n20/D 1.454 |
| Flash Point | >230 °F |
Quality Assurance
We adhere to strict quality control protocols to guarantee consistency across every batch. Each production lot undergoes rigorous analysis using gas chromatography and other validated methods to confirm identity and purity. A Certificate of Analysis (COA) is provided with every shipment, detailing test results against our factory standards. Our facility maintains optimal storage conditions to preserve chemical integrity prior to dispatch.
Industrial Applications
- Organic Synthesis: Used extensively as a protecting group reagent for alcohols and diols.
- Pharmaceutical Intermediates: Supports the synthesis of complex active pharmaceutical ingredients (APIs).
- Agrochemical Production: Serves as a building block in the manufacture of pesticide intermediates.
- Material Science: Employed in the modification of surfaces and polymer synthesis.
Storage and Handling
This compound is moisture-sensitive and should be handled under inert atmosphere conditions such as nitrogen or argon. For long-term stability, store in a tightly closed container within a cool, dry environment at 2-8°C. Ensure adequate ventilation during use and wear appropriate personal protective equipment to prevent exposure to vapors or liquid contact.
