Intermediates

N,N'-Dicyclohexylcarbodiimide

  • CAS No.538-75-0
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity N,N'-Dicyclohexylcarbodiimide (DCC) serves as a premier condensation reagent for peptide synthesis and organic dehydration processes.

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Product Technical Details

Product Overview

N,N'-Dicyclohexylcarbodiimide, commonly abbreviated as DCC, is a highly versatile organic compound widely recognized for its exceptional efficacy as a condensation and dehydrating agent in modern chemical synthesis. With the CAS registry number 538-75-0, this reagent plays a pivotal role in facilitating the formation of amide, ester, and anhydride bonds. Our manufacturing process ensures that every batch meets stringent quality control standards, delivering consistent performance for demanding laboratory and industrial applications. The compound is characterized by its stability and reactivity, making it an indispensable tool for chemists engaged in complex molecular construction.

Technical Specifications

ParameterSpecification
Chemical NameN,N'-Dicyclohexylcarbodiimide
CAS Number538-75-0
Molecular FormulaC13H22N2
Molecular Weight206.33 g/mol
Purity (GC)≥99.0%
AppearanceWhite crystal or light yellow liquid
Melting Point24-35°C
Density1.247 g/cm³
HS Code2925290090

Industrial Applications

The primary utility of N,N'-Dicyclohexylcarbodiimide lies in its capacity to activate carboxylic acids for nucleophilic attack, a fundamental step in peptide coupling reactions. Beyond pharmaceutical synthesis, it is extensively utilized in the production of polymers, agrochemicals, and fine chemicals where dehydration is required. The reagent effectively converts acids into reactive O-acylisourea intermediates, which subsequently react with amines or alcohols to form the desired products. Key application areas include:

  • Peptide synthesis and protein modification
  • Esterification reactions in organic chemistry
  • Preparation of acid anhydrides
  • Dehydration of primary amides to nitriles
  • Chemical research and development laboratories

Safety and Storage

Proper handling and storage are essential to maintain the integrity of this chemical product. N,N'-Dicyclohexylcarbodiimide should be stored in a cool, ventilated area away from direct sunlight and moisture to prevent hydrolysis. The material is classified under Hazard Class 6.1 with UN Number 2992, indicating that it requires careful handling to avoid potential health risks associated with exposure. We recommend using appropriate personal protective equipment during handling. Our packaging options include 25 kg drums, with customization available to meet specific logistical requirements. Each shipment is accompanied by a Certificate of Analysis (COA) to verify compliance with stated specifications.