1,3-Diisopropylcarbodiimide

Product Overview

1,3-Diisopropylcarbodiimide, commonly known as DIC, is a premier carbodiimide reagent widely utilized in modern organic synthesis and pharmaceutical manufacturing. As a critical dehydration condensation agent, it facilitates the formation of amide bonds with high efficiency and minimal racemization. Our premium grade product is manufactured under strict quality control standards to ensure consistent performance in sensitive chemical reactions. This reagent is particularly valued for its solubility profile and reaction kinetics, making it a preferred choice for complex molecule assembly.

Key Features And Advantages

• High Chemical Purity: Guaranteed ≥99.0% purity by GC analysis for reliable reaction outcomes.
• Optimized Reactivity: Designed for efficient coupling in peptide synthesis and esterification processes.
• Low Odor Formulation: Improved handling characteristics compared to traditional carbodiimide reagents.
• Stable Supply Chain: Consistent bulk availability from a certified global manufacturer.
• Comprehensive Documentation: Full COA and technical support provided with every shipment.

Technical Specifications

Industrial Applications

This specialized chemical intermediate serves as a fundamental building block in the synthesis of pharmaceuticals, peptides, and fine chemicals. It is extensively used in solid-phase peptide synthesis (SPPS) where it activates carboxylic acids for nucleophilic attack by amines. Beyond peptide chemistry, it functions effectively in esterification reactions and the preparation of acid anhydrides. The versatility of DIC makes it indispensable in research laboratories and large-scale production facilities focusing on advanced organic synthesis. Its compatibility with various solvents enhances its utility across different process conditions.

Storage And Handling

To maintain optimal quality, 1,3-Diisopropylcarbodiimide should be stored in a cool, ventilated area away from direct sunlight and moisture. Containers must be kept tightly sealed when not in use to prevent hydrolysis. Proper personal protective equipment, including gloves and eye protection, is recommended during handling. The product is classified under Hazard Class 6.1 and should be transported according to relevant safety regulations. Our packaging options include 20 kg drums, with custom solutions available to meet specific logistical requirements. Adherence to these storage guidelines ensures the longevity and efficacy of the reagent for your manufacturing processes.