1,4-Difluorobenzene
- CAS No.540-36-3
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High purity 1,4-Difluorobenzene (CAS 540-36-3) designed for advanced organic synthesis and pharmaceutical intermediate applications with guaranteed quality.
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Product Overview
1,4-Difluorobenzene, also known as p-Difluorobenzene, is a critical fluorinated aromatic compound widely utilized in the fine chemical and pharmaceutical industries. As a key building block, this substance serves as an essential precursor for the synthesis of complex organic molecules, including agrochemicals, pharmaceuticals, and advanced materials. Our manufacturing process ensures exceptional purity levels, making it an ideal choice for researchers and industrial producers who demand consistency and reliability in their chemical reactions.
The introduction of fluorine atoms into organic structures often significantly enhances the metabolic stability and bioavailability of final products. Consequently, high-quality 1,4-Difluorobenzene is indispensable for modern medicinal chemistry programs focused on developing novel therapeutic agents. We adhere to strict quality control protocols to guarantee that every batch meets or exceeds international standards for organic synthesis intermediates.
Key Physical and Chemical Properties
Understanding the physical characteristics of 1,4-Difluorobenzene is vital for safe handling and effective integration into synthesis pathways. This compound typically presents as a colourless to pale yellow transparent liquid with a distinct aromatic odor. Its specific density and boiling point facilitate efficient distillation and purification processes during downstream manufacturing. The chemical stability of the fluorine-carbon bond provides robustness during various reaction conditions, allowing for versatile functionalization strategies.
- High chemical stability under standard storage conditions
- Excellent solubility in common organic solvents
- Consistent boiling point range for precise distillation
- Low moisture content to prevent hydrolysis side reactions
Quality Specifications and Analysis
We maintain rigorous testing standards to ensure product integrity. Each production lot undergoes comprehensive analysis using gas chromatography and other advanced analytical techniques. The following table outlines the typical specifications and test results associated with our premium grade 1,4-Difluorobenzene.
| Items of Analysis | Standard of Analysis | Test Results |
|---|---|---|
| Appearance | Light yellow to yellow liquid | Conform |
| Assay (GC) | ≥99.00% | 99.82% |
| Water Content | ≤0.5% | 0.06% |
| Conclusion | Conforms to Factory Standard | |
Industrial Applications
The primary application of 1,4-Difluorobenzene lies in its role as an organic synthesis intermediate. It is frequently employed in nucleophilic aromatic substitution reactions where the fluorine atoms act as leaving groups or directing motifs. Pharmaceutical companies utilize this intermediate to construct fluorinated drug candidates, leveraging the unique electronic properties of fluorine to optimize drug-receptor interactions. Additionally, it finds use in the production of specialized polymers and liquid crystals where thermal stability and dielectric properties are paramount.
Packaging and Storage Guidelines
To preserve the quality of 1,4-Difluorobenzene during transit and storage, proper handling procedures must be followed. The product is typically packaged in 200 kg drums, though custom packaging solutions are available to meet specific logistical requirements. Storage should be conducted in a cool, ventilated area away from direct sunlight and incompatible materials such as strong oxidizing agents. Containers must remain tightly sealed to prevent moisture absorption and contamination. Our logistics team ensures secure shipping compliance with international hazardous material regulations where applicable.
