Intermediates

1,4-Dioxaspiro[4.5]decan-8-one

  • CAS No.4746-97-8
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity 1,4-Dioxaspiro[4.5]decan-8-one intermediate for pharmaceutical and liquid crystal synthesis. Reliable supply with COA.

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Product Technical Details

Product Overview

1,4-Dioxaspiro[4.5]decan-8-one is a highly specialized organic intermediate characterized by its unique spirocyclic ketal structure. This compound serves as a critical building block in advanced organic synthesis, particularly within the pharmaceutical and materials science sectors. Our manufacturing process ensures exceptional consistency and purity, making it an ideal choice for researchers and industrial producers who demand reliable chemical performance. The molecule features a cyclohexanedione backbone protected by an ethylene ketal group, which provides stability during various synthetic transformations.

As a key precursor, this chemical facilitates the construction of complex molecular architectures. Its structural integrity allows for selective reactions, enabling chemists to introduce functional groups with high precision. Whether used in the development of novel therapeutic agents or high-performance liquid crystal materials, the quality of the starting intermediate directly impacts the efficiency and yield of the final product. We prioritize rigorous quality control to meet the stringent requirements of modern chemical manufacturing.

Technical Specifications

ParameterValue
Chemical Name1,4-Dioxaspiro[4.5]decan-8-one
CAS Number4746-97-8
Molecular FormulaC8H12O3
Molecular Weight156.18 g/mol
Purity>99%
AppearanceWhite powder
Melting Point70-73 °C
Boiling Point112 °C
Density1.16 g/cm3
Refractive Index1.489

Industrial Applications

This intermediate is extensively utilized in the synthesis of pharmaceutical active ingredients. Its role often involves serving as a protected ketone equivalent, allowing for multi-step synthesis routes where specific functional group tolerance is required. The stability of the ketal moiety ensures that downstream reactions proceed without unwanted side reactions, thereby improving overall process safety and efficiency. In the pharmaceutical industry, consistency in raw material quality is paramount, and our product delivers the reliability needed for regulatory compliance.

Beyond pharmaceuticals, 1,4-Dioxaspiro[4.5]decan-8-one is valuable in the production of liquid crystal materials. The rigid spirocyclic structure contributes to the desired mesogenic properties required for high-performance displays. Manufacturers in this sector require intermediates with minimal impurities to ensure the optical and electrical characteristics of the final liquid crystal mixture meet industry standards. Our production capabilities are scaled to support both research-scale quantities and bulk industrial demands.

Quality Assurance And Storage

Every batch of 1,4-Dioxaspiro[4.5]decan-8-one undergoes comprehensive analytical testing. We employ advanced chromatography and spectroscopy methods to verify purity and structural identity. A Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality parameters. This transparency allows our clients to integrate our materials into their supply chains with confidence. Our facility adheres to strict operational protocols to prevent contamination and ensure product integrity from synthesis to packaging.

Proper storage is essential to maintain the chemical stability of this intermediate. The product should be kept in a cool, dry, and well-ventilated area, protected from direct light and moisture. Containers must remain tightly sealed when not in use to prevent hydrolysis of the ketal group. Under recommended conditions, the material maintains its specified properties over extended periods. We offer flexible packaging options, including standard drums and customized solutions based on client logistics requirements.

Why Partner With Us

  • Consistent high purity levels exceeding 99% for reliable synthesis outcomes.
  • Comprehensive technical support and documentation including COA and MSDS.
  • Scalable production capacity to meet both R&D and bulk manufacturing needs.
  • Global shipping logistics with secure packaging to ensure safe delivery.
  • Competitive bulk pricing structures for long-term partnership agreements.