Intermediates

1,4-Dithiane-2,5-diol

  • CAS No.40018-26-6
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity 1,4-Dithiane-2,5-diol is a critical pharmaceutical intermediate used primarily in the synthesis of nucleoside analogs. We offer bulk quantities with verified COA and global logistics support.

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Product Technical Details

Product Overview

1,4-Dithiane-2,5-diol, also known commercially as p-Dithiane-2,5-diol, represents a specialized organic compound essential within the pharmaceutical synthesis landscape. As a cyclic dithiane derivative, this molecule serves as a fundamental building block for constructing complex heterocyclic structures found in modern antiviral medications. Our facility specializes in the production of this high-grade intermediate, ensuring consistent quality that meets the rigorous demands of pharmaceutical manufacturing partners worldwide.

The compound is characterized by its stable crystalline structure and specific reactivity profile, making it an ideal precursor for multi-step organic synthesis. We maintain strict control over every batch to guarantee that the chemical integrity remains uncompromised from production to delivery.

Physical And Chemical Properties

Understanding the physicochemical characteristics of 1,4-Dithiane-2,5-diol is vital for process chemists integrating this material into their synthesis routes. The compound exhibits a defined molecular weight and thermal stability profile suitable for standard industrial processing conditions. Below are the key technical parameters verified through our quality control laboratories.

PropertyValue
Molecular FormulaC4H8O2S2
Molecular Weight152.235 g/mol
Density1.5 ± 0.1 g/cm3
Boiling Point360.9 ± 42.0 °C at 760 mmHg
Melting Point130 °C (dec.)
Flash Point175.5 ± 26.6 °C
Vapour Pressure0.0 ± 1.8 mmHg at 25°C
Index Of Refraction1.689

Quality Specifications

For pharmaceutical intermediates, purity is not merely a metric but a requirement for regulatory compliance and downstream reaction efficiency. Our production process utilizes advanced purification techniques to minimize impurities and moisture content. Each shipment is accompanied by a comprehensive Certificate Of Analysis (COA) detailing the test results against our internal specifications.

Specification ItemStandard
AppearanceWhite to off-white crystalline powder
Assay (Purity)≥ 98.0%
Moisture Content≤ 0.5%

Industrial Applications

The primary application of 1,4-Dithiane-2,5-diol lies in the synthesis of nucleoside analogs, which are critical components in antiviral therapies. Specifically, it acts as a key intermediate in the manufacturing process of Lamivudine. The unique dithiane ring structure facilitates specific protection and deprotection strategies during the assembly of the final active pharmaceutical ingredient.

Beyond antiviral drugs, this chemical building block is utilized in various research and development projects focused on heterocyclic chemistry. Its reliability in synthesis routes makes it a preferred choice for process development teams aiming to optimize yield and reduce waste in large-scale production.

Packaging And Storage

To preserve the chemical stability of 1,4-Dithiane-2,5-diol, proper handling and storage protocols must be observed. We offer flexible packaging solutions designed to protect the material from environmental factors such as humidity and light during transit.

  • Standard Packaging: 25 kg per drum.
  • Custom Packaging: Available upon customer request to suit specific logistics needs.
  • Storage Conditions: Store in a cool, ventilated place away from direct sunlight and moisture.
  • Safety: Handle with appropriate personal protective equipment as per standard chemical safety guidelines.

Our commitment to quality extends beyond the product itself. We provide global shipping capabilities and dedicated technical support to ensure seamless integration of our intermediates into your supply chain. Contact our sales team for current bulk pricing and availability.