1-(4-Iodophenyl)piperidin-2-one
- CAS No.385425-15-0
- GradeIndustrial / Pharmaceutical
- Availabilityβ In Stock
High-purity pharmaceutical intermediate used in the synthesis of antithrombotic agents. Available in bulk quantities with full documentation.
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Product Overview
1-(4-Iodophenyl)piperidin-2-one is a specialized organic compound widely recognized for its critical role in modern medicinal chemistry. As a key pharmaceutical intermediate, this substance serves as an essential building block in the multistep synthesis of complex therapeutic agents. Our facility produces this compound under strict quality control protocols to ensure consistency and reliability for research and development purposes as well as large-scale manufacturing needs.
The presence of the iodine substituent on the phenyl ring provides unique reactivity profiles, making it highly valuable for cross-coupling reactions and other transformation processes required in advanced drug discovery. We understand the importance of supply chain stability for active pharmaceutical ingredient production, which is why we maintain robust inventory levels and streamlined logistics capabilities.
Quality Specifications
Quality assurance is the cornerstone of our manufacturing process. Every batch undergoes rigorous analytical testing to verify compliance with international standards. The following table outlines the typical specifications for this product:
| Parameter | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity (HPLC) | Greater than or equal to 98.5 percent |
| Single Impurity | Less than or equal to 0.5 percent |
| Total Impurity | Less than or equal to 1.0 percent |
| Moisture Content | Less than or equal to 0.5 percent |
| Melting Point | 118 to 120 degrees Celsius |
| Molecular Formula | C11H12INO |
| Molecular Weight | 301.12 g/mol |
Industrial Applications
This chemical intermediate is primarily utilized in the pharmaceutical sector for the synthesis of antithrombotic medications. Its structural properties facilitate specific cyclization and amidation reactions necessary for constructing complex heterocyclic frameworks. Researchers and process chemists value this material for its high reactivity and consistent performance during scale-up operations.
Beyond direct API synthesis, this compound is also employed in method development and optimization studies within laboratory settings. The high purity grade ensures minimal interference during analytical procedures, allowing for accurate data collection and reproducible results. Our technical team supports clients with detailed documentation including certificates of analysis and safety data sheets.
Manufacturing and Synthesis
Our production methodology involves precise amidation and cyclization steps using high-quality raw materials. We utilize 4-Iodoaniline and 5-Bromovaleryl Chloride as starting materials under controlled conditions to maximize yield and minimize byproduct formation. The process is optimized to reduce environmental impact while maintaining economic efficiency.
We adhere to good manufacturing practices throughout the production cycle. Regular equipment calibration and personnel training ensure that every batch meets the stringent requirements of our global partners. Continuous improvement initiatives are in place to enhance process safety and product quality over time.
Packaging and Storage
Standard packaging consists of 25 kg drums designed to protect the material from moisture and light exposure. Custom packaging solutions are available upon request to meet specific client logistics requirements. Proper storage conditions include keeping the container tightly closed in a cool, dry, and well-ventilated area away from incompatible substances.
We offer global shipping services with comprehensive tracking to ensure timely delivery. Our commitment to customer satisfaction extends beyond the point of sale, providing ongoing support for any technical inquiries or supply chain adjustments needed for your project success.
