Intermediates

1-[(4-Nitrophenyl)methyl]-1,2,4-triazole

  • CAS No.119192-09-5
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity pharmaceutical intermediate used in the synthesis of advanced therapeutic agents. Available in bulk quantities with comprehensive quality documentation.

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Product Technical Details

Product Overview

1-[(4-Nitrophenyl)methyl]-1,2,4-triazole is a specialized organic compound serving as a critical building block in the pharmaceutical industry. This heterocyclic intermediate features a triazole ring substituted with a nitrophenyl methyl group, providing unique reactivity profiles essential for complex multi-step synthesis pathways. Our facility produces this chemical under strict quality control protocols to ensure consistency and reliability for downstream API manufacturing.

As a key precursor in the production of specific migraine therapeutics, this compound demands high precision in its molecular structure. We utilize advanced catalytic processes to achieve superior regioselectivity and minimize impurity profiles. The resulting product supports efficient coupling reactions and facilitates the construction of more complex pharmacophores required for modern medicinal chemistry applications.

Technical Specifications

Our manufacturing process adheres to international standards for fine chemicals and pharmaceutical intermediates. Each batch undergoes rigorous analytical testing using HPLC, NMR, and mass spectrometry to verify identity and purity. The physical properties are optimized to ensure ease of handling during large-scale production runs.

ParameterValue
CAS Number119192-09-5
Molecular FormulaC9H8N4O2
Molecular Weight204.19 g/mol
AppearanceWhite to light yellow powder
Assay (Purity)≥98.0%
Density1.39 g/cm3
Boiling Point433.4°C at 760 mmHg
Flash Point215.9°C

Industrial Applications

This triazole derivative is primarily utilized as an intermediate in the synthesis of Rizatriptan benzoate and related pharmaceutical active ingredients. Its structural integrity is vital for ensuring the efficacy and safety of the final medicinal product. Chemical manufacturers and research institutions rely on this material for developing new therapeutic formulations and optimizing existing production lines.

  • Essential building block for triptan-class pharmaceutical synthesis.
  • Compatible with various nucleophilic substitution and reduction reactions.
  • Supports scalable manufacturing processes for API production.
  • Used in research and development of neurological therapeutic agents.

Quality Assurance and Safety

We prioritize safety and compliance throughout the supply chain. Our quality assurance team issues a Certificate of Analysis (COA) with every shipment, detailing batch-specific test results. The material is packaged in durable containers to prevent moisture absorption and contamination during transit. Proper storage in a cool, ventilated environment ensures long-term stability and maintains chemical integrity.

Our global logistics network ensures timely delivery while adhering to all hazardous material transportation regulations. We offer flexible packaging options, including standard 25 kg drums or custom configurations based on client requirements. Partner with us for a reliable supply of high-performance chemical intermediates designed to meet the demanding standards of the pharmaceutical industry.